Results 91 to 100 of about 2,688,047 (379)

Infecção hospitalar e causas múltiplas de morte Nosocomial infection and multiple causes of death

Jornal de Pediatria, 2002
Objetivo: este estudo se propôs a avaliar a possibilidade de se obter informações de infecção hospitalar por meio da declaração de óbito. Material e métodos: foi feita revisão de prontuários de crianças que faleceram com mais de 48 horas de internação ...
Ruth N.T. Turrini, Augusto H. Santo
doaj   +1 more source

Long‐Term Evaluation of Givinostat in Duchenne Muscular Dystrophy, and Natural History Comparisons

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives This ongoing, open‐label extension study is evaluating the long‐term safety, tolerability, and efficacy of givinostat, a Class I and II histone deacetylase inhibitor, in patients with Duchenne muscular dystrophy (DMD). Methods The recruited patients completed one of two prior clinical studies (one Phase 2 and one Phase 3 [EPIDYS ...
Craig M. McDonald, Michela Guglieri, Dragana Vučinić, Gyula Acsadi, John F. Brandsema, Claudio Bruno, Erika L. Finanger, Amy Harper, Mercedes Lopez Lobato, Riccardo Masson, Nuria Muelas, Francina Munell, Yoram Nevo, Yann Péréon, Han Phan, Valeria A. Sansone, Mariacristina Scoto, Tracey Willis, Richard S. Finkel, Krista Vandenborne, Sara Cazzaniga, Silvia Montrasio, Federica Alessi, Paolo Bettica, Eugenio Mercuri, for the Givinostat Study 51 Investigators, the Cooperative International Neuromuscular Research Group (CINRG) Duchenne Natural History Study (DNHS) Investigators, the ImagingDMD Investigators, Enrico Bertini, Giacomo Pietro Comi, Eugenio Maria Mercuri, Giuseppe Vita, Sonia Messina, Claudio Bruno, Riccardo Masson, Valeria Sansone, Nathalie Goemans, Liesbeth De Waele, Laurent Servais, Teresa Gidaro, Odile Boespflug‐Tanguy, Yann Péréon, Jessika Johannsen, Astrid Blaschek, Ulrike Schara‐Schmidt, Erik Niks, Imelda de Groot, Saskia Houwen‐van Opstal, Andres Nascimento, Juan Jesus Vilchez, Nuria Muelas, Francina Munell, Marcos Madruga Garrido, Mercedes Lopez Lobato, Michaela Guglieri, Tracey Willis, Stefan Spinty, Daniel Hawcutt, Mariacristina Scoto, Jean K. Mah, Laura McAdam, Kathryn Selby, Katherine Mathews, Craig McDonald, Craig Zaidman, Barry Byrne, John Brandsema, Gyula Acsadi, Chamindra Laverty, Amy Harper, Erika Finanger, Han Phan, Yoram Nevo, Vedrana Milic Rasic, Dragana Vucinic   +74 more
wiley   +1 more source

Certification of Death in Singapore [PDF]

Proceedings of Singapore Healthcare, 2014
Proper certification of death has legal, social, and epidemiological significance. There is unfortunately little in the existing medical literature relevant to such an important issue in Singapore. With the implementation of the Coroners Act 2010, there has been recent surge in interest in this matter, highlighting a need for additional instruction on
Siang Hui Lai, Serene Ai Kiang Ong
openaire   +2 more sources

Durability of Response to B‐Cell Maturation Antigen‐Directed mRNA Cell Therapy in Myasthenia Gravis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We report the 12‐month follow‐up outcomes from a Phase 2 clinical trial (NCT04146051) evaluating Descartes‐08, a BCMA‐directed RNA chimeric antigen receptor T‐cell (rCAR‐T) therapy for refractory generalized myasthenia gravis (MG).
Nizar Chahin, Gregory Sahagian, Marc H. Feinberg, C. Andrew Stewart, Christopher M. Jewell, Metin Kurtoglu, Miloš D. Miljković, Tuan Vu, Tahseen Mozaffar, James F. Howard Jr, the MG‐001 Study Group   +10 more
wiley   +1 more source

Causes of death certification of adults: an exploratory cross-sectional study at a university hospital in Riyadh, Saudi Arabia

Annals of Saudi Medicine, 2012
BACKGROUND AND AIMS: Saudi Arabia has no precise data on causes of death. We sought to ascertain the commonest causes of death as stated in death certificates of adults and evaluate the completeness of death certificates at a teaching hospital in Riyadh.
Lubna A. Ansary, Samia A. Esmaeil, Yaser A. Adi   +2 more
doaj   +1 more source

Classification of cancer-related death certificates using machine learning.

Australasian Medical Journal, 2013
BACKGROUND Cancer monitoring and prevention relies on the critical aspect of timely notification of cancer cases. However, the abstraction and classification of cancer from the free-text of pathology reports and other relevant documents, such as death ...
Luke Butt, G. Zuccon, Anthony N. Nguyen, Anton Bergheim, Narelle Grayson   +4 more
semanticscholar   +1 more source

Contribution of respiratory tract infections to child deaths: a data linkage study [PDF]

, 2014
Background: Respiratory tract infections (RTIs) are an important cause of death in children, and often contribute to the terminal decline in children with chronic conditions.
A Gittelsohn, AG Barnett, AGSC Jansen, AJ van Hoek, AL Braga, BG Williams, D Salisbury, DM Fleming, G Maudsley, HF Guite, I Rudan, JR Panickar, K Kristensen, K Mulholland, KJ O'Malley, KM Neuzil, LA Johansson, LA Johansson, M Eriksson, Mario Cortina-Borja, MT Osterholm, N Sachedina, Nirupa Dattani, NJ Andrews, P Hardelid, Pia Hardelid, RJ Pitman, Ruth Gilbert, SN Ladhani, T Andabaka   +29 more
core   +2 more sources

Inhibition of Glutamine Metabolism Attenuates Tumor Progression Through Remodeling of the Macrophage Immune Microenvironment

Advanced Biology, EarlyView.
The prodrug strategy used in this study offers new promise for cancer metabolism‐based therapies. JHU083, a prodrug that, when cleaved by protease in the tumor microenvironment, yields the glutamine antagonist DON. JHU083 inhibits tumor growth by targeting glutamine‐addicted cancer cells and suppressing glutamine‐dependent M2 macrophages, leading to a ...
Tianhe Li, Sepehr Akhtarkhavari, Sumeng Qi, Jiawei Fan, Tu‐Yung Chang, Yao‐An Shen, JinMing Yang, Barbara S. Slusher, Ie‐Ming Shih, Stephanie Gaillard, Tian‐Li Wang   +10 more
wiley   +1 more source

Does quality control of death certificates in hospitals have an impact on cause of death statistics?

Tidsskrift for Den Norske Laegeforening, 2013
BACKGROUND The effects of inaccurate death certificates on cause of death statistics are uncertain. Since 2008, Akershus University Hospital has systematically corrected all death certificates. The effects of these corrections on the total cause of death
G. C. Alfsen, L. Lyckander
semanticscholar   +1 more source

The death registers of the registrar general as sources for social and demographic history [PDF]

, 1980
There can be little doubt that some of the most promising data for socio-historical demographic research can be found in the keeping of each state's Registrar General.
Durey, M.
core   +1 more source