Results 111 to 120 of about 264,423 (290)
Advanced Science, EarlyView.ABSTRACT Background & Aims: Cancer‐associated fibroblasts (CAFs) drive immunosuppression in hepatocellular carcinoma (HCC). However, their metabolic regulation remains poorly defined. We investigated the role of nicotinamide N‐methyltransferase (NNMT) in CAFs. Approach & Results: High NNMT expression in CAF tissues was confirmed by western blotting and
Shounan Lu +20 more
wiley +1 more source
Advanced Science, EarlyView.Gastric cancer‐derived exosomal TAGLN2 is identified as a key mediator of vascular reprogramming, with significantly elevated levels detected in patient serum. Independent of canonical SEMA4D signaling, it nucleates a cytoplasmic TAGLN2/NRP1/SEMA4D ternary complex that dually activates YAP, promoting angiogenesis, vascular dysfunction, and metastasis ...
Shuqi Yu +7 more
wiley +1 more source
COVID-19 Death Determination Methods, Minnesota, USA, 2020–2022
Emerging Infectious DiseasesAccurate and timely mortality surveillance is crucial for elucidating risk factors, particularly for emerging diseases. We compared use of COVID-19 keywords on death certificates alone to identify COVID-19 deaths in Minnesota, USA, during 2020–2022 ...
Lydia J. Fess +14 more
doaj +1 more source
Iowa Office of the State Medical Examiner Newsletter, September 1, 2008, no. 4 [PDF]
, 2008 The official newsletter of the Iowa Office of the State Medical ...
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Effect of marital status on death rates. Part 2: Transient mortality spikes
, 2015 We examine what happens in a population when it experiences an abrupt change in surrounding conditions. Several cases of such "abrupt transitions" for both physical and living social systems are analyzed from which it can be seen that all share a common ...
Richmond, Peter, Roehner, Bertrand M.
core +3 more sources
Advanced Science, EarlyView.This study reports the development of a fully humanized bispecific T cell engager targeting IL13RA2, a tumor‐associated antigen enriched in glioblastoma. This off‐the‐shelf immunotherapy drives potent, antigen‐dependent T cell activation and tumor killing, and prolongs survival in experimental GBM and other solid tumors models without detectable off ...
Joseph T. Duffy +16 more
wiley +1 more source
Advanced Science, EarlyView.This study outlines the developmental pipeline of a multiplexed nanozyme‐based lateral flow immunoassay for the purpose of ovarian germ cell tumor detection. It demonstrates the application of a design of experiments optimization approach for nanozyme probe conjugate development.
Aida Abdelwahed +10 more
wiley +1 more source
Inequality in individual mortality and economic conditions earlier in life [PDF]
We analyze the effect of being born in a recession on the mortality rate later in life in conjunction with social class. We use individual data records from Dutch registers of birth, marriage, and death certificates, covering the period 1815-2000, and we
Lindeboom, Maarten +2 more
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We only die once… but from how many causes? [PDF]
, 2016 When a person dies, the certifying physician records the cause of death on the death certificate. In many cases, several causes are mentioned, as well as the train of events that led to death.
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