Results 71 to 80 of about 2,688,047 (379)
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine+10 more
wiley +1 more source
Identification of pneumonia and influenza deaths using the death certificate pipeline
Background Death records are a rich source of data, which can be used to assist with public surveillance and/or decision support. However, to use this type of data for such purposes it has to be transformed into a coded format to make it computable ...
Davis Kailah+4 more
doaj +1 more source
The purpose of this review is to assess the extent to which dementia is omitted as a cause of death from the death certificates of patients with dementia.
J. P. Romero+3 more
semanticscholar +1 more source
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton+17 more
wiley +1 more source
Maternal deaths databases analysis: Ecuador 2003-2013
Background: Maternal mortality ratio in Ecuador is the only millennium goal on which national agencies are still making strong efforts to reach 2015 target.
Antonio Pino+3 more
doaj +1 more source
Quality comparison of electronic versus paper death certificates in France, 2010
BackgroundElectronic death certification was established in France in 2007. A methodology based on intrinsic characteristics of death certificates was designed to compare the quality of electronic versus paper death certificates.MethodsAll death ...
D. Lefeuvre+6 more
semanticscholar +1 more source
Declining mortality from congenital heart disease in Malta [PDF]
Congenital heart disease (CHD) is the most common congenital anomaly occurring in approximately 10/1000 live births. Analysis of official Maltese Health Division statistics listing CHD as the primary cause of death on death•certificates has shown a ...
Attard Montalto, Simon+2 more
core
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed+8 more
wiley +1 more source
Group Life Insurance: Its Legal Aspects [PDF]
Background: Female representation on boards is an ongoing debate. The European Parliament voted in November 2013 in favour of a proposal that it should be at least 40 percent women on company boards by 2020.
Gustavsson, Jenny, Skeppstedt, Maria
core +3 more sources