ABSTRACT Immune checkpoint inhibitors (ICIs) frequently cause thyroid immune‐related adverse events (irAEs). Permanent hypothyroidism, the clinically most relevant phenotype, requires lifelong hormone replacement. We investigated its incidence, course, risk factors, and prognostic relevance under pembrolizumab.
Freya Koffka +9 more
wiley +1 more source
An NLR-VOZ seesaw: from asymmetric selection to synthetic broad-spectrum resistance. [PDF]
Su Y, Zang S, Sun T, You C, Que Y.
europepmc +1 more source
The Impact of Economic Growth on Insurance (Growth)
ABSTRACT This paper investigates the impact of economic growth on insurance (growth), focusing on the outflow side of the insurance activity, as captured by benefits (including commissions and expenses). The findings provide evidence that economic growth does exert a positive, statistically significant impact on the benefit side of insurance (growth ...
Nicholas Apergis +2 more
wiley +1 more source
COVID-19 and Suicide Mortality in a Population-Based Medico-Legal Registry: An Interrupted Time-Series and Changepoint Analysis from Southeast Romania. [PDF]
Piraianu AI +6 more
europepmc +1 more source
Abstract Background The choice of tocolytic drugs is one of the most debated aspects of preterm birth management. Objective This network meta‐analysis aimed to establish an evidence‐based hierarchy for tocolytics used in preterm labor by evaluating their efficacy in delaying delivery, safety, and neonatal outcomes.
Barbara Gardella +5 more
wiley +1 more source
The Paradox of Performativity: Latent Depression as a Crisis in the Contemporary Psychosocial Context. [PDF]
Aghakhani N, Lopez V, Goh YS.
europepmc +1 more source
Abstract Objective To evaluate the association between gender‐based violence (GBV) assessed in early pregnancy and adverse perinatal outcomes using relative and absolute effect measures in an urban low‐ and middle‐income setting. Methods We conducted a prospective cohort study including 3890 singleton pregnancies recruited from two public healthcare ...
Elsa Romelia Moreno‐Verduzco +6 more
wiley +1 more source
LASSO-based nomogram to predict early treatment failure in advanced hepatocellular carcinoma treated with SBRT, lenvatinib, and tislelizumab. [PDF]
Zhao Y +5 more
europepmc +1 more source
The female journey following sexual assault: Medical care, law enforcement and judicial outcomes
Abstract Objective Sexual violence affects 22% of Australian women, posing health and justice challenges. Systemic failures, fragmented data, and low conviction rates hinder effective responses. This study integrates Australian Capital Territory (ACT) medical and policing datasets to examine victim characteristics and case progression from clinical ...
Vanita Parekh +7 more
wiley +1 more source
Does Psychological Flexibility Correlate with Mystical Experiences: A Machine Learning Approach Including State of Surrender, Near-Death Experiences, and Psilocybin Consumption. [PDF]
Briggs D, Sease TB, Menou R, Perkins DR.
europepmc +1 more source

