Results 51 to 60 of about 29,882 (253)

Abstract Representation of Movement Parameters in Basal Ganglia Output

open access: yesAdvanced Science, EarlyView.
The basal ganglia output provides a scalable velocity/position signal across behavioral contexts, supporting the idea that these variables are represented in the brain as abstract entities rather than as fixed changes in joint angles or specific sets of body effectors.
Ana Silvia Báez‐Cordero   +3 more
wiley   +1 more source

Abolition or mitigation of the death penalty - A perspective on the laws of Israel

open access: yesIn die Skriflig, 1994
The issue concerning the topic of the death penalty for capital offences is still widely discussed. Those supporting the retention of the death penalty mostly quote the Old Testament as their source of authority.
F. N. Lion-Cachet
doaj   +1 more source

A Metabolic‐Epigenetic Axis of AARS1/IGF2BP3‐K280 Lactylation Sustains Endometrial Cancer Stemness and Recurrence

open access: yesAdvanced Science, EarlyView.
Lactate‐driven endometrial cancer relapse is mediated by enzymatic protein modification. Elevated lactate levels activate AARS1, which catalyzes K280 lactylation of IGF2BP3, therefore stabilizing HMGA2 mRNA and promoting tumor stemness and recurrence.
Peng Jiang   +11 more
wiley   +1 more source

Discourse on the Death Penalty: A Study of Public Perceptions in Indonesia

open access: yesYustisia
The current debate over the death penalty between the retentionist and abolitionist groups is addressed in Decision Number 2-3/PUU-V/2007 of Indonesia, establishing a middle ground.
Prija Djatmika   +2 more
doaj   +1 more source

SLC25A4high Hepatocytes Enhance Lifestyle Intervention Response in MASLD by Recruiting Eating Macrophages

open access: yesAdvanced Science, EarlyView.
SLC25A4high hepatocytes drive metabolic‐associated steatotic liver disease (MASLD) remission by recruiting lipid‐eating macrophages. The hepatocyte Slc25a4/PANX1/ATP/P2ry12 axis mediates find‐me signaling that triggers macrophage recruitment and efferocytosis, while recruited macrophages secrete GDF15 to activate hepatocyte PPARα and promote fatty acid
Yiting Qian   +8 more
wiley   +1 more source

The Problem of the Legislative Sentence to the Death Penalty in Russia in the Context of International Obligations

open access: yesМосковский журнал международного права, 2015
Legislative Sentence to the death penalty as an exceptional measure of capital punishment and its relation to the right to life have been a subject of public discussion for a long time, and nowadays they are topical ones for every civilized state.
Alexey V. Ivanov
doaj   +1 more source

Drug Repurposing for Treating NCOR‐Related Intellectual Disability

open access: yesAdvanced Science, EarlyView.
An autism‐associated NCOR1 heterozygous mutation upregulates NRGs and activates NRG backward signaling in hypothalamic GABAergic neurons in mouse models, leading to Gabra2 downregulation and cognitive deficits, which can be therapeutically targeted by repurposing FDA‐approved drugs.
Yan Kong   +15 more
wiley   +1 more source

THE DEATH PENALTY FORMULATION POLICY ON THE NARCOTICS CRIME ACT IN INDONESIA

open access: yesJurnal IUS, 2014
The International narcotic criminal acts are at a dangerous level of society,  state and nation even world peace. In efforts to overcome the narcotic criminal act through criminal law instrument,  the Indonesian government has adopted a policy by issuing
I Wayan Wardana
doaj   +1 more source

Meningeal Lymphatic LTBR Deficiency Links Spinal Cord Injury to Secondary Brain Pathology

open access: yesAdvanced Science, EarlyView.
Spinal cord injury (SCI) induces remote brain alterations beyond the injured spinal cord. This study links dysfunction of meningeal lymphatic vessels (mLVs) to neuroinflammation and neuronal injury after SCI. LTBR‐mediated lymphatic restoration improves meningeal lymphatic integrity and neurological outcomes, highlighting LTBR as a potential regulator ...
Yi Chen   +12 more
wiley   +1 more source

Disabling COMPASS Promoter Licensing Shifts HDAC‐Inhibited Gastric Cancer Toward Sustained Transcriptional Suppression During Recovery

open access: yesAdvanced Science, EarlyView.
Combined inhibition of the WDR5 WIN pocket and HDAC activity converts SAHA‐induced hyperacetylation into a promoter state with reduced WDR5–COMPASS association and H3K4me3. MYC/E2F‐linked nascent transcription and biosynthetic recovery are suppressed, while apoptosis and senescence‐like features increase, resulting in sustained growth inhibition in ...
Jintian Song   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy