Results 151 to 160 of about 16,408,492 (298)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Factors influencing the prevalence and death rate of COPD: a pan-database ecological study covering 201 countries and regions from 1990 to 2021. [PDF]

EClinicalMedicine
Wang Z, Cao W, You Z, Li S, Xue M, Li H, Lin J, Cai G, Chen Y, Liang Z, Zhou C, Wu X, Dong G, Zhong N, Sun B, Cheng ZJ.   +15 more
europepmc   +1 more source

Ecologic study of influenza vaccination uptake and COVID-19 death rate in New York City. [PDF]

BMC Public Health, 2022
Moreland A, Gillezeau C, Eugene A, Alpert N, Taioli E.   +4 more
europepmc   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Reduction in finisher pig death rate on a farm in Japan following use of a commercial killed vaccine against porcine reproductive and respiratory syndrome virus. [PDF]

J Vet Med Sci
Yonezawa Y, Nakagami T, Tsutsumi N, Momma N, Taira O, Matsuyama R, Makita K.   +6 more
europepmc   +1 more source

COVID-19 Incidence and Death Rate in Epilepsy: Too Early to Tell? [PDF]

Epilepsy Curr, 2021
Vossler DG.
europepmc   +1 more source

Blacks’ Death Rate Due to Circulatory Diseases Is Positively Related to Whites’ Explicit Racial Bias

Psychology Science, 2016
Jordan B. Leitner, Eric Hehman, O. Ayduk, Rodolfo Mendoza-Denton   +3 more
semanticscholar   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

Impact of hydatid cyst laminated layer antigens on cell death rate, apoptosis induction, and key genes in the cell proliferation pathway: Insights from A549 cell line studies. [PDF]

PLoS One
Hosseini E, Tavakoli-Yaraki M, Meamar AR, Ajam Z, Alipour M, Bagga R, Razmjou E, Rafiei-Sefiddashti R.   +7 more
europepmc   +1 more source

Racial bias is associated with ingroup death rate for Blacks and Whites: Insights from Project Implicit.

Social Science & Medicine (1967), 2016
Jordan B. Leitner, Eric Hehman, O. Ayduk, Rodolfo Mendoza-Denton   +3 more
semanticscholar   +1 more source