Results 71 to 80 of about 16,408,492 (298)
DEMOGRAPHIC SPASMS – A LIMIT OF SUSTAINABLE TERRITORIAL DEVELOPMENT. CASE STUDY: THE DISTRICT OF CICEU [PDF]
Studia Universitatis Babeş-Bolyai: Geographia, 2015 Demographic Spasms – A Limit of Sustainable Territorial Development. Case Study: The District (“Ținut”)2 of Ciceu. Human component is currently the most precious resource, the only one which can generate production and consumption, fact that makes it ...
ALEXANDRA-CAMELIA POTRA
doaj
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
An Investigation of the Mortality Caused by Accidents and Incidents in Babol Based on the International Classification of Diseases (ICD10) [PDF]
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i BābulBackground and Objective: Accidents as the second cause of disability and the main cause of disability and death can lead to physical and mental disorders and even death.
F Farajpour +6 more
doaj
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Folia Horticulturae, 2020 The current study investigated the effects of gamma radiation on the death rate, morphological traits and meiotic abnormalities in ground-grown chrysanthemum ‘Donglinruixue’, and inter-simple sequence repeat (ISSR) markers were used to identify the DNA ...
Wang Ling +3 more
doaj +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
The Parkinson’s disease death rate: carbidopa and vitamin B6
Clinical Pharmacology : Advances and Applications, 2014 The only indication for carbidopa and benserazide is the management of L-3,4-dihydroxyphenylalanine (L-dopa)-induced nausea. Both drugs irreversibly bind to and permanently deactivate pyridoxal 5′-phosphate (PLP), the active form of vitamin B6, and PLP ...
M. Hinz, A. Stein, T. Cole
semanticscholar +1 more source
Case Fatality Rate of Cancer Patients with COVID-19 in a New York Hospital System
Cancer Discovery, 2020 Patients with cancer in a New York hospital system were much more vulnerable to COVID-19 death than the general population, with a case fatality rate that varied by cancer type and was 28% overall.
V. Mehta +18 more
semanticscholar +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
BMC Gastroenterology, 2014 BackgroundFew studies have compared the prognosis and liver-related mortality in patients with NAFLD (nonalcoholic fatty liver disease) and AFLD (alcoholic fatty liver disease). We aimed to investigate the etiology and liver-related mortality of patients
Svanhildur Haflidadottir +6 more
semanticscholar +1 more source