Results 61 to 70 of about 713,984 (284)

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Investigating the Challenges of Death Registration and Classification Program and Providing a Solution: A Qualitative Study

open access: yesمجله اپیدمیولوژی ایران, 2022
Background and Objectives: The distribution of causes of death indicates the distribution of risk factors for death, and is a basis of planning and intervention to reduce risk factors.
M Gholamhoseinzadeh   +3 more
doaj  

The disappearance of the "revolving door" patient in Scottish general practice: successful policies [PDF]

open access: yes, 2012
<b>Background</b> We describe the health of "revolving door" patients in general practice in Scotland, estimate changes in their number over the timescale of the study, and explore reasons for changes, particularly related to NHS and ...
Andrea E Williamson   +12 more
core   +4 more sources

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Myanmar mortality registration: an assessment for system improvement

open access: yesPopulation Health Metrics, 2017
Background The vital registration system in Myanmar has a long history and geographical coverage is currently high. However, a recent assessment of vital registration systems of 148 countries showed poor performance of the death registration system in ...
Myitzu Tin Oung   +3 more
doaj   +1 more source

Reviewing disease burden among rural Indian women [PDF]

open access: yes, 2004
The disease burden of rural Indian women is reviewed by utilizing the data from the 'Survey of Causes of Death (rural)' annual reports of Registrar General of India supplemented with National family health survey (NFHS-II).
Agnihotram V, Dr. Ramanakumar
core  

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

Spartan Daily, February 7, 1983 [PDF]

open access: yes, 1983
Volume 80, Issue 6https://scholarworks.sjsu.edu/spartandaily/6988/thumbnail ...
San Jose State University, School of Journalism and Mass Communications
core   +3 more sources

Home - About - Disclaimer - Privacy