Results 121 to 130 of about 17,472,109 (310)

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Bertol Extract Combined with 5-Fluorouracil Synergistically Suppresses the Growth of Esophageal Squamous Cell Carcinoma Cells

open access: yesNatural Product Communications
Background: Esophageal cancer is a prevalent malignancy of the digestive tract with a high incidence rate in Asia. Esophageal squamous cell carcinoma (ESCC) is the most common histological type, accounting for more than 90% of cases.
Hong-Wei Gao   +5 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

JNDS, Volume 27, Number 3

open access: yes, 2008
Letter from Robert G. Mays to the editor of the Journal of Near-Death Studies on the following topic "On the Scope of Analysis for the AWARE Study.
Mays, Robert G., Mays, Suzanne B.
core   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

JNDS, Volume 22, Number 2

open access: yes, 2003
Letter written to the editor of the Journal of Near-Death Studies on the topic: "Making Meaning of Frightening NDEs.
Atwater, P. M. H.
core   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Arkansas Coalition to Abolish the Death Penalty records

open access: yes, 1978
This collection contains ACADP correspondence, memos, newsletters, board minutes, news clippings, and brochures.
Arkansas Coalition to Abolish the Death Penalty
core   +1 more source

JNDS, Volume 22, Number 1

open access: yes, 2003
Letter from Janice Miner Holden to the editor of the Journal of Near-Death Studies announcing the availability of a new electronic tool, the Near-Death Experience Research Bibliography, Part ...
Holden, Janice Miner
core   +1 more source

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

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