Results 181 to 190 of about 2,579,652 (218)

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Beta-blocker therapy after myocardial infarction: an umbrella review. [PDF]

EClinicalMedicine
Cataldo-Miranda P, Cao PK, Koh HJW, Gasevic D, Chodapuneedi S, Eliakundu AL, Romero L, Stub D, Zoungas S, Kaye DM, Talic S.   +10 more
europepmc   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Meaning and Influencing Factors of a Good Death for Community-Dwelling Individuals With Dementia: An Integrative Review. [PDF]

Int J Older People Nurs
Park JS, Cho H, Park WS, Kim H.
europepmc   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

RIPK 1 in Alzheimer's Disease: Research Progress Integrating Pathogenesis on Necroptosis-Related Neuroinflammation, and Potential Therapeutic Strategies. [PDF]

Biomedicines
Toklucu ES, Shen S, Wang C, Zhang C.
europepmc   +1 more source

Assessment of the Effectiveness of Early Versus Delayed Invasive Strategies in Non-ST Elevation Myocardial Infarction (NSTEMI): A Systematic Review and Meta-Analysis. [PDF]

Cureus
Kamble A, Revunuru NR, Rangachari B, Bharat Patel V, Ullah I, Ahmed Z.   +5 more
europepmc   +1 more source

Cardiovascular Implications of Diabetes Mellitus: A Systematic Literature Review. [PDF]

Cureus
Gupta PK, Sekar G A, Diwakar R, Panchal NA, Kumar A, Bhaumik A.   +5 more
europepmc   +1 more source