Results 71 to 80 of about 5,333,729 (314)
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa +3 more
wiley +1 more source
Using the life-course metaphor in Richard M. Dorson’s landmark address “The Birth of American Studies” in Warsaw on the occasion of forty years since the start of the groundbreaking Harvard program in American Studies, this essay questions whether ...
Simon J. Bronner
doaj +1 more source
Mitochondrial fusion and Bid-mediated mitochondrial apoptosis are perturbed by alcohol with distinct dependence on its metabolism [PDF]
Environmental stressors like ethanol (EtOH) commonly target mitochondria to influence the cell’s fate. Recent literature supports that chronic EtOH exposure suppresses mitochondrial dynamics, central to quality control, and sensitizes mitochondrial ...
Hajnóczky, György +4 more
core +3 more sources
ABSTRACT Introduction Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.
Masataka Ueda +15 more
wiley +1 more source
The Digital Afterlife: Web Cemeteries and Their Potential for Sport History
Death notices and obituaries have existed for centuries and have been democratized to include ordinary people previously deemed unworthy of public commemoration.
David Christopher Galindo
doaj +1 more source
Sex-related differences in death control of somatic cells [PDF]
In 2001, The United States Institute of Medicine (IOM) Committee on Understanding the Biology of Sex and Gender Differences concluded that ‘Sex…should be considered when designing and analysing studies in all areas and at all levels of biomedical and ...
FILIPPINI, Antonio +3 more
core +2 more sources
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
The p53-MDM2 network: from oscillations to apoptosis [PDF]
The p53 protein is well-known for its tumour suppressor function. The p53-MDM2 negative feedback loop constitutes the core module of a network of regulatory interactions activated under cellular stress.
Bose, Indrani, Ghosh, Bhaswar
core +2 more sources
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Queer Death Studies: Coming to Terms with Death, Dying and Mourning Differently. An Introduction
This special issue aims to rethink death, dying and mourning through theoretical and methodological modes of queering. These modes are mobilised under three overarching themes: (1) queer (necro)politics, which focuses not only on regimes and technologies
Marietta Radomska +2 more
doaj +1 more source

