Results 81 to 90 of about 5,333,729 (314)

Does the use of specialist palliative care services modify the effect of socioeconomic status on place of death? A systematic review [PDF]

, 2015
© SAGE Publications. Background: Cancer patients in lower socioeconomic groups are significantly less likely to die at home and experience more barriers to access to palliative care.
Allgar, Victoria, Chen, Hong, Dalgliesh, Christopher, Johnson, Miriam, MacLeod, Una, Nicolson, Donald J.   +5 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

GLOBAL DIGITAL DEATH AND GLOCAL DYING: THEORETICAL CHALLENGES AND POSSIBLE RESEARCH DIRECTIONS

Glocalism: Journal of Culture, Politics and Innovation
This paper discusses the possibilities of using theories of glocalisation for understanding national differences in death ways, in times when global digital technologies play a growing role in how individuals and societies respond to severe crises. How
ADELA TOPLEAN
doaj   +1 more source

Pramanicin analog induces apoptosis in human colon cancer cells: critical roles for Bcl-2, Bim, and p38 MAPK signaling [PDF]

, 2013
Pramanicin (PMC) is an antifungal agent that was previously demonstrated to exhibit antiangiogenic and anticancer properties in a few in vitro studies. We initially screened a number of PMC analogs for their cytotoxic effects on HCT116 human colon cancer
Başağa, Hüveyda, Bodur, Çağrı, Harrison, Paul, Isimjan, Tayirjan T., Karslı, Gizem, Kütük, Özgür   +5 more
core   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

A Bayesian geoadditive relative survival analysis of registry data on breast cancer mortality [PDF]

, 2006
In this paper we develop a so called relative survival analysis, that is used to model the excess risk of a certain subpopulation relative to the natural mortality risk, i.e. the base risk that is present in the whole population.
Held, Leonhard, Hennerfeind, Andrea
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Comparing unplanned and potentially planned home deaths: a population-based cross-sectional study

BMC Palliative Care, 2018
Background There is little research on number of planned home deaths. We need information about factors associated with home deaths, but also differences between planned and unplanned home deaths to improve end-of-life-care at home and make home deaths a
Camilla Kjellstadli, Bettina Sandgathe Husebø, Hogne Sandvik, Elisabeth Flo, Steinar Hunskaar   +4 more
doaj   +1 more source

Deep Sequencing Analysis of RNAs from Citrus Plants Grown in a Citrus Sudden Death-Affected Area Reveals Diverse Known and Putative Novel Viruses. [PDF]

, 2017
Citrus sudden death (CSD) has caused the death of approximately four million orange trees in a very important citrus region in Brazil. Although its etiology is still not completely clear, symptoms and distribution of affected plants indicate a viral ...
Coletta-Filho, Helvecio D, Dorta, Silvia O, Falk, Bryce W, Machado, Marcos A, Matsumura, Emilyn E, Nerva, Luca, Nouri, Shahideh, Oliveira, Tiago S   +7 more
core   +3 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source