Results 151 to 160 of about 400,556 (315)

High‐Yield Bioproduction of Extracellular Vesicles from Stem Cell Spheroids via Millifluidic Vortex Transport

open access: yesAdvanced Materials, EarlyView.
Stem cell spheroids, produced via a high‐throughput microfabrication technique, are transported within a vortex generated at the outlet channels of a cross‐slot millifluidic chip. For Reynolds number exceeding 170–200, intermittent high shear stresses applied to each spheroid within the vortex trigger a massive release of biologically active ...
Elliot Thouvenot   +8 more
wiley   +1 more source

Porous Silicon Nanoneedles Efficiently Deliver Adenine Base Editor to Correct a Recurrent Pathogenic COL7A1 Variant in Recessive Dystrophic Epidermolysis Bullosa

open access: yesAdvanced Materials, EarlyView.
Base editing using nanoneedles efficiently corrects pathogenic variants in the type VII collagen gene of primary fibroblasts from patients with recessive dystrophic epidermolysis bullosa. Nanoneedle editing induces minimal and reversible transcriptional perturbations while restoring the production and secretion of functional type VII collagen.
Salman Ahmad Mustfa   +10 more
wiley   +1 more source

Debris disks around M dwarfs: The Herschel DEBRIS survey [PDF]

open access: yesarXiv
The Herschel open-time key program Disc Emission via a Bias-free Reconnaissance in the Infrared and Sub-millimeter (DEBRIS) is an unbiased survey of the nearest ~100 stars for each stellar type A-M observed with a uniform photometric sensitivity to search for cold debris disks around them.
arxiv  

Off‐The‐Shelf Multivalent Nanoconjugate Cancer Vaccine Rescues Host Immune Response against Melanoma

open access: yesAdvanced Materials, EarlyView.
A star‐shaped cross‐linked polyglutamate (StCl) nanocarrier delivers melanoma‐associated peptide antigens via redox‐responsive linkers, inducing lymph node‐targeted antigen presentation. The nanoconjugate activates dendritic cells, promotes effector T‐cell responses, and enables tumor regression even in humanized patient‐derived preclinical models ...
Liane IF Moura   +19 more
wiley   +1 more source

Correlation of space debris observations by the virtual debris algorithm

open access: yes, 2009
The main problem in the orbit determination of the space debris population is the correlation of independently ob- served tracklets, that are sets of observations over a short time. The information contained in such data are not suf- ficient for a complete determination of an orbit, thus we need to find two or more tracklets belonging to the same ...
TOMMEI, GIACOMO   +3 more
openaire   +3 more sources

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