Results 81 to 90 of about 1,045,539 (348)

Cleaning ability of toothbrush with or without the use of dentifrice on debris and plaque removal in hostel inmates aged 20-24 years

open access: yesJournal of Indian Association of Public Health Dentistry, 2014
Objectives: The aim was to find the cleaning ability of the toothbrush with or without the use of dentifrice in removal of debris and plaque in hostel inmates aged 20-24 years.
Sachin Chand, Jitender Solanki
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Feasibility of transit photometry of nearby debris discs [PDF]

open access: yes, 2014
Dust in debris discs is constantly replenished by collisions between larger objects. In this paper, we investigate a method to detect these collisions.
Kalas, P.   +2 more
core   +3 more sources

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Marine Debris Survey Manual [PDF]

open access: yes, 1992
Over the last several years, concern has increased about the amount of man-made materials lost or discarded at sea and the potential impacts to the environment. The scope of the problem depends on the amounts and types of debris.
Dixon, Trevor R.   +2 more
core   +2 more sources

A 2MASS All-Sky View of the Sagittarius Dwarf Galaxy: IV. Modeling the Sagittarius Tidal Tails

open access: yes, 2004
M giants recovered from the Two Micron All-Sky Survey (2MASS) have recently been used to map the position and velocity distributions of tidal debris from the Sagittarius (Sgr) dwarf spheroidal galaxy entirely around the Galaxy.
David R. Law   +9 more
core   +2 more sources

Sediment-moss interactions on a temperate glacier: Falljökull, Iceland [PDF]

open access: yes, 1999
Full text of this article can be found at: http://www.igsoc.org/annals/ Copyright IGS. DOI: 10.3189/172756408784700734We present the results of preliminary investigations of globular moss growth on the surface of Falljökull, a temperate outlet glacier of
Baum, R   +7 more
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Investigation of the Effect of Debris-Induced Damage for Constructing Tsunami Fragility Curves for Buildings

open access: yesGeosciences, 2018
Catastrophe models quantify potential losses from disasters, and are used in the insurance, disaster-risk management, and engineering industries. Tsunami fragility and vulnerability curves are key components of catastrophe models, providing probabilistic
Joshua Macabuag   +3 more
doaj   +1 more source

Resolved Debris Discs Around A Stars in the Herschel DEBRIS Survey [PDF]

open access: yes, 2012
The majority of debris discs discovered so far have only been detected through infrared excess emission above stellar photospheres. While disc properties can be inferred from unresolved photometry alone under various assumptions for the physical ...
Booth, Mark   +14 more
core   +6 more sources

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