Results 51 to 60 of about 72,341 (283)

Role of Debris Cover in the Thermal Physics of Glaciers [PDF]

Journal of Glaciology, 1986
AbstractA mathematical model is presented of non-stationary melting processes of ice including particles of morainic material. The problem is treated as a Stephen-type one with the phase boundary of ice melting being located under the debris cover. The main terms of the heat-balance equation for a glacier surface are solar radiation and convective heat
A. N. Bozhinskiy, M. S. Krass, V. V. Popovnin   +2 more
openaire   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Debris flows and debris avalanches initiation and runout susceptibility assessment in Campania region (Italy) [PDF]

, 2023
Sectors of the Campania region (southern Italy), where pyroclastic airfall deposits cover carbonate slopes, have frequently experienced debris avalanches and debris flows.
Mazza Davide, Mazza D., De Vita P., Tufano Rita, Russo G., Guadagno F. M., Guadagno Francesco Maria, Russo Giacomo, Revellino Paola, De Vita Pantaleone, Tufano R., Revellino P.   +11 more
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Meteorology and surface energy fluxes in the 2005–2007 ablation seasons at the Miage debris-covered glacier, Mont Blanc Massif, Italian Alps

, 2010
During the 2005–2007 June–September ablation seasons, meteorological conditions were recorded on the lower and upper parts of the debris‐covered ablation zone of Miage Glacier, Italy. In 2005, debris temperature and subdebris ice melt were also monitored
Mihalcea, Claudia, Diolaiuti, Guglielmina, G.A. Diolaiuti, Brock, Ben W., Kirkbride, Martin P., M. Kirkbride, C.E. Mihalcea, Cutler, Mark E. J.; id_orcid, C. Smiraglia, M. E. J. Cutler, Cutler, Mark, Brock, Benjamin, Kirkbride, Martin, Smiraglia, Claudio, B. W. Brock   +14 more
core   +1 more source

Brief communication: Supraglacial debris-cover changesin the Caucasus mountains [PDF]

, 2019
Debris cover on glaciers can significantly alter melt, and hence, glacier mass balance and runoff. Debris coverage typically increases with shrinking glaciers.
Bolch, Tobias; https://orcid.org/, Kutuzov, Stanislav S; https://orcid.org/, Lavrentiev, Ivan I; https://orcid.org/, Wheate, Roger D, Zemp, Michael; https://orcid.org/, Tielidze, Levan G; https://orcid.org/   +5 more
core   +1 more source

Reduced melt on debris-covered glaciers: investigations from Changri Nup Glacier, Nepal [PDF]

The Cryosphere, 2016
Approximately 25 % of the glacierized area in the Everest region is covered by debris, yet the surface mass balance of debris-covered portions of these glaciers has not been measured directly. In this study, ground-based measurements of surface elevation
C. Vincent, P. Wagnon, J. M. Shea, W. W. Immerzeel, P. Kraaijenbrink, D. Shrestha, A. Soruco, Y. Arnaud, F. Brun, E. Berthier, S. F. Sherpa   +10 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Air temperature distribution and energy balance modelling of a debris-covered glacier

, 2016
Near-surface air temperature is an important determinant of the surface energy balance of glaciers that is often represented by constant linear temperature gradients in models.
Brock, B.W., Shaw, Thomas, Shaw, Thomas E., Diotri, Fabrizio, Pellicciotti, F., Brock, Ben W., Diotri, F., Shaw, T.E., Fyffe, Catriona, Rutter, Nick, Rutter, N., Fyffe, Catriona L., Brock, Benjamin, Pellicciotti, Francesca   +13 more
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source