Results 91 to 100 of about 14,509 (263)
Advanced Science, EarlyView.Alzheimer's disease (AD) is the most common neurodegenerative disorder. This study demonstrates that microglial Rack1 deficiency decreased Aβ deposition and neuroinflammation and ameliorated cognitive impairments in AD model mice by enhancing IGF1‐mediated astrocytic phagocytosis.
Jingdan Zhang +13 more
wiley +1 more source
Advanced Science, EarlyView.Intervertebral disc degeneration is triggered by ACSL4 accumulation‐mediated ferroptosis of nucleus pulposus cells due to CMA dysfunction. KAT2B promotes ACSL4 degradation via CMA through acetylation. AAV‐mediated LAMP2A delivery or engineered exosomes rescue nucleus pulposus cell senescence and disc degeneration.
Zhouwei Wu +10 more
wiley +1 more source
Secret of Longevity: Protoplanetary Disks as a Source of Gas in Debris Disks
The Astrophysical JournalWhile protoplanetary disks (PPDs) are generally thought to disperse within several million years, recent observations have revealed gas in their older counterparts, debris disks.
Wataru Ooyama +4 more
doaj +1 more source
A Multifaceted Spatial Analysis of Tomb Distribution in Blemmyan Berenike (Eastern Desert of Egypt)
Archaeological Prospection, EarlyView.ABSTRACT This study examines the spatial and visual organisation of tombs in the post–Roman Berenike located in Egypt's Eastern Desert. Archaeological surveys, remote sensing, geophysical methods, excavations and GIS‐based analyses are used for a comprehensive understanding of the spatial patterns and cultural significance behind the positions and ...
Mariusz Gwiazda +4 more
wiley +1 more source
BMEMat, EarlyView.A double‐positive surface marker detection approach was developed to conduct exosome surface protein detection in serum samples. It reaches single‐exosome detection, and over 300 exosome protein parameters are analyzed. The diagnostic accuracy achieved 90% in differentiation of high‐grade serous/serous ovarian carcinoma patients, benign patients, and ...
Jiaoyan Qiu +7 more
wiley +1 more source
The Astrophysical JournalThe theoretical debris supply rate from a tidal disruption of stars can exceed about 100 times of Eddington accretion rate for a 10 ^6−7 M _⊙ supermassive black hole.
Yuehua Zhang +4 more
doaj +1 more source
A COMPREHENSIVE DUST MODEL APPLIED TO THE RESOLVED BETA PICTORIS DEBRIS DISK FROM OPTICAL TO RADIO WAVELENGTHS [PDF]
, 2016 Nicholas P. Ballering +7 more
openalex +1 more source
Rosemary Essential Oil Microemulsion for Fungal Keratitis Treatment
Chemistry &Biodiversity, EarlyView.ABSTRACT This study investigated the use of Rosmarinus officinalis (rosemary) essential oil in a microemulsion (ME) formulation for the treatment of ocular fungal keratitis, a serious infection that can lead to blindness. The ME was characterized in terms of pH, stability, homogeneity, osmolarity, and other physicochemical properties.
Saulo Ribeiro +5 more
wiley +1 more source
The Nearby, Young, χ1 Fornacis Cluster: Membership, Age, and an Extraordinary Ensemble of Dusty Debris Disks [PDF]
, 2019 B. Zuckerman, Beth Klein, Joel Kastner
openalex +1 more source
Deep Underground Science and Engineering, EarlyView.This paper investigates the high‐pressure water jet‐pick combined rock‐breaking mode (HPC), which employs high‐pressure water jets to precut grooves on both sides of the picks. The rock‐breaking patterns and performance of the HPC method are obtained, and the auxiliary rock‐breaking mechanism of water jet grooving is revealed.
Jingjing Lu +6 more
wiley +1 more source