Results 181 to 190 of about 14,837 (310)

Synergistic antiviral activity against human adenovirus through combination of itraconazole and brincidofovir

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Human adenovirus (HAdV) causes respiratory or gastrointestinal tract infections depending on the virus subtype. While HAdV infections are generally self‐limiting in immunocompetent people, they can result in significant morbidity and mortality in immunocompromised adults and children.
Mohamed Zamzamy   +16 more
wiley   +1 more source

Evidence for a sub-Jovian planet in the young TWA 7 disk. [PDF]

open access: yesNature
Lagrange AM   +28 more
europepmc   +1 more source

Antimicrobial‐Releasing Implant Substrates for Combating Oral Biofilms: An In Vitro Study

open access: yesClinical Oral Implants Research, EarlyView.
ABSTRACT Background and Objectives Peri‐implantitis, a biofilm‐associated inflammatory disease, significantly threatens dental implant longevity. Current treatments face limitations due to biofilm robustness. This study evaluates the efficacy of antimicrobial‐releasing titanium‐silica (Ti/SiO2) composite implant systems against multispecies oral ...
Nur Hidayatul Nazirah Kamarudin   +7 more
wiley   +1 more source

Hcfc1 and Ogt Mediate Zebrafish CNS Regeneration Through Hippo/Yap Signalling

open access: yesCell Proliferation, EarlyView.
This work identifies Hcfc1 and Ogt as key regulators of zebrafish CNS regeneration through modulation of Hippo/Yap signalling. Loss of Hcfc1 or Ogt activity inhibition impairs regeneration, which is restored by Yap overexpression, revealing a new regulatory axis that enhances CNS regenerative capacity.
Priyanka P. Srivastava   +9 more
wiley   +1 more source

White dwarf systems: Exoplanets and debris disks

open access: yes
Although there is abundant and diverse observational evidence in support of white dwarf stars hosting planets or debris disks which form in the catastrophic destruction of various planetary bodies, the key processes that explain these observations are still being intensely investigated.
openaire   +2 more sources

AMSC‐sEVs Ameliorated Crohn's Disease by Inhibiting Macrophage‐Myofibroblast Transition Through the Delivery of MFGE8

open access: yesCell Proliferation, EarlyView.
Our study demonstrated that TGF‐β1 activated MAPK signalling pathway and promoted the MMT and secretion of CCL17 under CD‐associated intestinal inflammatory conditions. AMSC‐sEVs can deliver MFGE8, which inhibits MMT and CCL17‐mediated Treg recruitment by suppressing the MAPK signalling pathway, thereby alleviating intestinal fibrosis.
Minghao Xie   +6 more
wiley   +1 more source

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