Results 261 to 270 of about 14,837 (310)

Complex Mechanical Loading and Pro‐Inflammatory Cytokines in Intervertebral Disc Degeneration

JOR SPINE, Volume 9, Issue 1, March 2026.
This study investigated the combined effects of dynamic compression and torsion with major pro‐catabolic cytokine interleukin‐1 beta (IL‐1β) and its inhibitor: interleukin‐1 receptor antagonist (IL‐1Ra), on bovine IVD in an ex vivo organ culture system and further evaluated the mechanical effects using a subject‐personalized finite element model based ...
Katherine B. Crump, Estefano Muñoz‐Moya, Kim de Graaf, Paola Bermudez‐Lekerika, Nicole Schwendener, Wolf‐Dieter Zech, Christine L. Le Maitre, Jérôme Noailly, Benjamin Gantenbein   +8 more
wiley   +1 more source

Protocol for cell transplantation in Nematostella vectensis, a Hexacorallian model. [PDF]

STAR Protoc
Talice S, Barkan SK, Snyder GA, Kozlovski I, Sharoni T, Levy T, Lewandowska M, Ehrens D, Sultan E, Azarov A, Oisher S, Yannai R, Aharoni R, Hadad U, Davis C, Moran Y, Gershoni-Yahalom O, Traylor-Knowles N, Rosental B.   +18 more
europepmc   +1 more source

Influence of the Intervertebral Disc Microenvironment on Matrix Synthesis and Metabolism in Goat Nucleus Pulposus Cells

JOR SPINE, Volume 9, Issue 1, March 2026.
Goat nucleus pulposus cells cultured under clinically relevant oxygen, glucose, pH, and osmolarity revealed pH to have the most influential impact on viability and glycosaminoglycan synthesis. Interactions between factors showed that disc cell behavior is shaped by the microenvironment, highlighting its importance in regenerative therapy design for the
Niamh Wilson, Tara Ní Néill, Jake McDonnell, Emily McDonnell, Pieter A. J. Brama, Conor T. Buckley   +5 more
wiley   +1 more source

Experimental Investigation on Friction Behavior of Selective Laser Sintering Processed Parts. [PDF]

3D Print Addit Manuf
Rajendran P, Ganesan A.
europepmc   +1 more source

Responses of Root Microbiome and Metabolome Are Linked to Crop Disease Severity

Journal of Sustainable Agriculture and Environment, Volume 5, Issue 1, March 2026.
ABSTRACT Plant microorganisms are an essential component of the host and perform critical functions in plant development and health. Emerging evidence shows that plants use their root exudates to recruit beneficial microbes that protect them against abiotic and biotic stresses, including diseases.
Ayomide Emmanuel Fadiji, Brajesh K. Singh   +1 more
wiley   +1 more source

Tribological Performance of EPDM and TPV Elastomers Against Glass Fiber-Reinforced Polyamide 66 Composites. [PDF]

Materials (Basel)
Foltuț D, Uțu ID, Șerban VA.
europepmc   +1 more source

Unconventional Secretion of Angiogenic Sonic Hedgehog–Containing Extra‐Large Extracellular Vesicles is Driven by PI3K–Rab18‐GDP Signalling

Journal of Extracellular Biology, Volume 5, Issue 2, February 2026.
Human mesenchymal stem cells conditionally secrete sonic hedgehog (SHH)‐containing extra‐large extracellular vesicles (XLEVs) upon PI3K activation, which enriches the GDP‐bound form of Rab18. Rab18‐GDP drives perinuclear maturation and polarized vertical release of SHH‐XLEVs via Hsp90α‐ and nSMase2‐dependent mechanisms.
Shuo Wang, Rio Imai, Yuya Kaneko, Yosuke Tanaka   +3 more
wiley   +1 more source

Preparation and Negative Staining for Visualization of Cyanoglobule Lipid Droplets Using Transmission Electron Microscopy. [PDF]

Bio Protoc
Susanto FA, Withrow A, Lundquist PK.
europepmc   +1 more source

Efficient and rapid isolation of native AMPA receptor complexes for cryo‐EM

Protein Science, Volume 35, Issue 2, February 2026.
Abstract Isolating native ion channels for structural characterization is routinely achieved by extraction from membrane fractions of tissue with prolonged mild detergent treatment. AMPA receptors (AMPARs), glutamatergic receptors that mediate fast excitatory transmission and synaptic plasticity, are coassembled with diverse auxiliary subunits and ...
Jumi Park, Eric Gouaux
wiley   +1 more source

Contact Load on the Current-Carrying Tribological Performance of Copper-Graphite Composites. [PDF]

Materials (Basel)
Ye J, Wang N, Wu H, Wang C, Kang X.
europepmc   +1 more source