Results 181 to 190 of about 187,375 (261)

Materials‐Guided Gene‐Ionizable Lipid Nanoparticles to Reverse Iron‐Associated Immune Resistance in Renal Cancer

Advanced Science, EarlyView.
ABSTRACT Iron overload is a common metabolic disturbance in cancer and contributes to poor outcomes in renal cell carcinoma (RCC), yet its effects on the tumour immune microenvironment remain unclear. Here we identify a previously unrecognized immunosuppressive axis in which iron overload downregulates the palmitoyltransferase ZDHHC12 in CD8+ T cells ...
Xin Jin, Yulong Hong, Chengliang Yin, Wanyang Guo, Yaxuan Wang, Ruijiang Zeng, Ruilin Liu, Zexian Ding, Xinlin Liu, Shangqing Ren, Qiyang Liang, Yaohui Wang, Xu Zhang, João Conde, Yuan Li, Xin Ma, Liangyou Gu   +16 more
wiley   +1 more source

Debris flow volume prediction model based on back propagation neural network optimized by improved whale optimization algorithm. [PDF]

PLoS One
Ni B, Li L, Lin H, Qiang Y, Wu H, Zhang Z, Zhang Y.   +6 more
europepmc   +1 more source

A new method for evaluating stony debris flow rainfall thresholds: the Backward Dynamical Approach. [PDF]

Heliyon, 2019
Rosatti G, Zugliani D, Pirulli M, Martinengo M.   +3 more
europepmc   +1 more source

Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair

Advanced Science, EarlyView.
We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing, Yang Yang, Zichen Hong, Chunhui Tian, Huiyu Chu, Susanne Clara Prokop, Hongwei Cai, Mingxia Gu, Jason Tchieu, Ken Mackie, Feng Guo   +10 more
wiley   +1 more source

Data Mining and Statistical Approaches in Debris-Flow Susceptibility Modelling Using Airborne LiDAR Data. [PDF]

Sensors (Basel), 2019
Lay US, Pradhan B, Yusoff ZBM, Abdallah AFB, Aryal J, Park HJ.   +5 more
europepmc   +1 more source

A Catalytic Osmium Redox Couple Collapses Cancer Redox Balance

Advanced Science, EarlyView.
A stable Os(III)/Os(IV) redox couple is developed to disrupt the tumor cell redox balance by concurrently catalyzing ROS generation and GSH depletion. Osmium‐treated cells exhibit multiple cell death pathways, including apoptosis, ferroptosis, and immunogenic cell death.
Wan‐Qiong Huang, Tao Huang, Yiming Hao, Gui‐Feng Huang, Yi‐Lang Yan, Xin Fang, Ying Chen, Xiao‐Long Wei, Wai‐Lun Man, Wen‐Xiu Ni   +9 more
wiley   +1 more source

A Method for Improving Controlling Factors Based on Information Fusion for Debris Flow Susceptibility Mapping: A Case Study in Jilin Province, China. [PDF]

Entropy (Basel), 2019
Dou Q, Qin S, Zhang Y, Ma Z, Chen J, Qiao S, Hu X, Liu F.   +7 more
europepmc   +1 more source

Flow behavior of debris flows in the upper stream on mountainous debris torrent

Sabo Gakkaishi, 2003
IMAIZUMI, Fumitoshi, TSUCHIYA, Satoshi, OHSAKA, Okihiro   +2 more
openaire   +1 more source

The RNA‐Binding Protein PARN Remodeled 3′ UTR Structure Defines Poly(A)‐Loading Sites to Mediate Immunoglobulin Homeostasis

Advanced Science, EarlyView.
ABSTRACT Class Switch Recombination (CSR) is essential for generating high‐affinity antibody isotypes from IgM during adaptive humoral responses. Despite well‐established roles for various transcription factors, whether CSR is subject to dedicated post‐transcriptional control represents a significant gap in knowledge.
Siyuan Sun, Chen Yang, Xiaoyu Wang, Naijing Hu, Shengyao Zhang, Xinchun Li, Yu Chen, Jianan Zhai, Xiangfeng Tang, Wei Lu, Chenxu Lu, Changchang Cao, Weiru Yu, Wenhao Wu, Xiaonan Nie, Fengchao Wang, Bing Fang, Fazheng Ren, Yixuan Li, Juan Chen   +19 more
wiley   +1 more source

Hazard Assessment of Debris-Flow along the Baicha River in Heshigten Banner, Inner Mongolia, China. [PDF]

Int J Environ Res Public Health, 2016
Cao C, Xu P, Chen J, Zheng L, Niu C.
europepmc   +1 more source