Results 201 to 210 of about 187,375 (261)
Xenogeneic Mitochondrial Transplantation Improves Selected Age‐Associated Phenotypes in Mice
Advanced Science, EarlyView.Yak‐derived xenogeneic mitochondrial transplantation improves selected age‐associated phenotypes in mice, enhances mitochondrial functional readouts, and engages host mitochondrial quality‐control pathways. Broad tissue biodistribution, increased ATP production and mtDNA copy number, reduced ROS levels and dysfunctional mitochondria, improved motility ...
Wenpeng Li +5 more
wiley +1 more source
Advanced Science, EarlyView.SLC25A13 is identified as an immunometabolic driver of triple‐negative breast cancer that sustains ferroptosis resistance and immune evasion through a STAT3–IFI6 circuit. Pharmacologic degradation of SLC25A13 restores ferroptosis sensitivity and enhances anti‐PD‐1 efficacy, highlighting a strategy to convert immune‐cold tumors into immunotherapy ...
Yingze Zhu +8 more
wiley +1 more source
MiR‐940 Suppresses Ferroptosis by Controlling Expression of Key Regulatory Genes
Advanced Science, EarlyView.A CRISPR‐based screening identified miR‐940 as a critical suppressor of ferroptosis in cancer. By coordinating the downregulation of pro‐ferroptotic genes with the upregulation of GPX4, miR‐940 establishes a regulatory network that protects against ferroptosis and correlates with poor clinical outcomes in distinct cancer entities.
Andrea Kolak +19 more
wiley +1 more source
An Integrated DNA Nanoprobe for Intranuclear Imaging and in Situ Profiling of OGG1 Activity
Advanced Science, EarlyView.The TP‐SA nanoprobe, integrating an AS1411 aptamer for nuclear delivery and a FRET array for signal amplification, enables real‐time tracking of nuclear OGG1 activity. It reveals cell‐line‐specific basal OGG1 levels and shows clinical promise using pneumonia patients’ lavage fluid.
Mingzhu Zhao +9 more
wiley +1 more source
Laboratory Investigation on the Impact Force of Large Boulders in Debris Flows. [PDF]
Sensors (Basel)Yi W, Yu B, Liu Q, Hu J, Zhou J.
europepmc +1 more source
Design and Study of a Microfluidic Chip for Two-Stage Sorting of Oil Wear Debris Based on Magnetophoretic. [PDF]
Micromachines (Basel)Xu Z, Zhang H, Shi H, Han W, Liu B.
europepmc +1 more source
Entrained debris records regrowth of the Greenland Ice Sheet after the last interglacial. [PDF]
Nat GeosciHolschuh N +7 more
europepmc +1 more source
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Debris Flow Syndrome: Injuries and Outcomes after the Montecito Debris Flow
The American Surgeon™, 2019On January 9, 2018, a catastrophic debris flow devastated Montecito, California. A 30-foot wall of boulders, mud, and debris ran down the hillsides at 15 miles per hour injuring dozens and causing 21 prehospital deaths. A retrospective review was conducted of the victims from the debris flow presenting to Cottage Health.
Sarah, Langdon +2 more
openaire +2 more sources
Debris flow in metropolitan area — 2011 Seoul debris flow
Journal of Mountain Science, 2013A large number of debris flows occurred simultaneously at around 8:30 to 8:50 a.m. on July 27, 2011, at the center of Seoul, Korea. This area is located in the southern part of Seoul and is a densely populated district. As a result of the debris flow event, 16 people were killed, 30 houses were buried, and 116 houses were damaged around Umyeon Mountain,
Chan-Young Yune +5 more
openaire +1 more source