Results 281 to 290 of about 506,489 (355)

The Tumor‐to‐Endothelial Transfer of FTO Promotes Vascular Remodeling and Metastasis in Nasopharyngeal Carcinoma

Advanced Science, EarlyView.
Integrated omics analysis of matched primary and liver metastatic NPC tumors reveals a unique NOTCH1+ CSC subpopulation exhibiting enhanced stemness properties and tumorigenic capacity. With in vitro and in vivo assays, exosomal transfer of tumor‐derived FTO from NOTCH1+ cells to the endothelium promotes vascular permeability and metastatic potential ...
Chun Wu, Xuefei Liu, Liwen Gu, Jingru Lian, Yuting Wang, Yixin Cheng, Lianhui Duan, Guanyin Huang, Siqi Chen, Boxi Zhao, Sailan Liu, Yufan Yang, Shuqian Zheng, Zijian Lu, Wanping Guo, Jianyang Hu, Wenjing Wang, Zhixiang Zuo, Haiqiang Mai, LinQuan Tang, Songfa Zhang, Feiqiu Wen, Xin Hong, Ling Guo   +23 more
wiley   +1 more source

New experimental configuration for investigation of debris accumulation effect on local scour at bridge pier and abutment. [PDF]

Sci Rep
Abousaeidi Z, Rahimpour M, Qaderi K, Ahmadi MM, Madadi MR.   +4 more
europepmc   +1 more source

A Cold Stress‐Activated Endocrine Sentinel Chemical Hormone Promotes Insect Survival via Mitochondrial Adaptations Through the Adipokinetic Hormone Receptor

Advanced Science, EarlyView.
Seasonal cold adaptation is vital for insect survival, yet the molecular mechanisms linking diapause to mitochondrial resilience remain largely unresolved. We identify ascaroside C9 (asc‐C9) as a key endocrine signal that enhances diapause survival during cold stress by activating the AKHR–PGC1α–UCP4 axis, thereby driving cold‐induced lipolysis and ...
Jiao Zhou, Junxian Chen, Hongxia Zhang, Lu Guo, Kevin Mai, Elijah Abraham, Dilip V. Prajapati, Yue Chang, Jing Ning, Xinchen Wang, Defeng Li, Dan‐Dan Zhang, Jianghua Sun, Rebecca A. Butcher, Lilin Zhao   +14 more
wiley   +1 more source

Human Atlas of Tooth Decay Progression: Identification of Cellular Mechanisms Driving the Switch from Dental Pulp Repair Toward Irreversible Pulpitis

Advanced Science, EarlyView.
Tooth decay progression transforms the dental pulp response from repair to fibrosis. At early stages, stromal cells reprogram to repair the extra cellular matrix (ECM), blood vessels, and nerves, remodel and grow, keeping repair possible. In advanced decay, hypoxia, and vessel regression, in complement with an immune switch, fuel nerve degeneration and
Hoang Thai Ha, Sofya Kosmynina, Amandine Verocq, Keremsah Ozen, Ines Tekia, Hugo Bussy, Marie Ramirez, Dima Sabbah, Chloe Goemans, Valerie Vandenbempt, Esteban N. Gurzov, Sumeet Pal Singh, Nicolas Baeyens   +12 more
wiley   +1 more source

Lying Down Nystagmus in Lateral Canal Paroxysmal Positional Vertigo. [PDF]

Audiol Res
Gufoni M, Ducci N, Bernacca D, Califano L, Casani AP.   +4 more
europepmc   +1 more source

The hazard of large debris flows. [PDF]

Sci Adv
Harvey EL, Hales TC, Horton AJ, Francis OR, Yang F, Liu J, Fan X.   +6 more
europepmc   +1 more source

Enhancing Permeability and Gas Extraction in Low-Permeability Coal Seams: A Study on Gas-Liquid Two-Phase Jet Technology. [PDF]

ACS Omega
Li Y.
europepmc   +1 more source

Sediment transport by Greenland's icebergs. [PDF]

Nat Commun
Pierce E, Overeem I, Hasholt B.
europepmc   +1 more source

Study on the Charge Characteristics and Migration Characteristics of Amorphous Alloy Core Debris. [PDF]

Materials (Basel)
Yu W, Guan X.
europepmc   +1 more source

Improved YOLOv8-SST for accurate detection of small floating objects in complex water environments. [PDF]

PLoS One
Dong H, Li J, He X, Zhang M.
europepmc   +1 more source