Results 291 to 300 of about 513,388 (355)

Legumain Restrains Granuloma Formation by Inhibiting mTORC1/STAT1‐Mediated M1 Macrophage Polarization in Sarcoidosis

Advanced Science, EarlyView.
Legumain (LGMN) is upregulated in macrophages during sarcoid‑like granuloma formation. Macrophage‑derived LGMN binds to integrin αvβ3 and suppresses mTORC1/STAT1 signaling to restrain M1 macrophage polarization. Intratracheal delivery of lipid nanoparticles carrying Lgmn plasmid DNA (pDNA) elevates LGMN expression and effectively attenuates pulmonary ...
Mengyuan Liu, Yueyin Han, Bingbing Xie, Lili Zhu, Wenxiu Xu, Yinzhen Han, Yue Liao, Shuwei Gao, Dingyuan Jiang, Jing Geng, Zhen Li, Yinan Hu, Huaping Dai   +12 more
wiley   +1 more source

Tailored Porous Bimetallic Nanozyme Platform for Full‐Cycle Therapeutics of Intestinal Ischemia/Reperfusion

Advanced Science, EarlyView.
ABSTRACT Intestinal ischemia/reperfusion (I/R) injury presents a biphasic pathology: an acute oxidative‐inflammatory phase leading to organ failure, and a recovery phase marked by mucosal dysfunction and bacterial translocation. The developed MPB@TA‐Cu‐Ma nanocomposite functions as a dual‐phase therapeutic platform with significant efficacy. It rapidly
Chenghao Qiu, Wenjing Xian, Mengxue Wang, Guozhi Zhao, Yanhuo Zhang, Zhiyu Zhou, Bo Sheng, Zhuo Zhen, Xie Liu, Shouwen Diao, Mengwei Tu, Chen Qiu, Huixian Wang, Jianbo Zhang, Peng Zhu, Tong Li   +15 more
wiley   +1 more source

Laboratory Investigation on the Impact Force of Large Boulders in Debris Flows. [PDF]

Sensors (Basel)
Yi W, Yu B, Liu Q, Hu J, Zhou J.
europepmc   +1 more source

Design and Study of a Microfluidic Chip for Two-Stage Sorting of Oil Wear Debris Based on Magnetophoretic. [PDF]

Micromachines (Basel)
Xu Z, Zhang H, Shi H, Han W, Liu B.
europepmc   +1 more source

Phagocytosis is crucial for brain repair. [PDF]

J Cereb Blood Flow Metab
Lyu J, Zhang W, Wu WC, Leak R, Chen J.
europepmc   +1 more source

Hydrometeorological triggers of debris flows derived from historical archives and tree-ring data: Insights from the Swiss National Park

Jiazhi Qie, Christophe Corona, Adrien Favillier, Stefanie Gubler, Tamara Estermann, Markus Stoffel   +5 more
openalex   +1 more source

A novel technique for preventing distal embolism during endovascular therapy for femoropopliteal lesions: The flow-controlled anti-embolic technique. [PDF]

J Vasc Surg Cases Innov Tech
Iida O, Yoshii D, Toyoshima T, Okina Y, Kurata N.   +4 more
europepmc   +1 more source

Remote sensing and process attribution uncertainties in the Dharali event. [PDF]

NPJ Nat Hazards
Bhardwaj A, Sam L, Ali SN, Ahmed R.
europepmc   +1 more source

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Debris Flow Syndrome: Injuries and Outcomes after the Montecito Debris Flow

The American Surgeon™, 2019
On January 9, 2018, a catastrophic debris flow devastated Montecito, California. A 30-foot wall of boulders, mud, and debris ran down the hillsides at 15 miles per hour injuring dozens and causing 21 prehospital deaths. A retrospective review was conducted of the victims from the debris flow presenting to Cottage Health.
Sarah, Langdon, Arianne, Johnson, Rohit, Sharma   +2 more
openaire   +2 more sources

Debris flow in metropolitan area — 2011 Seoul debris flow

Journal of Mountain Science, 2013
A large number of debris flows occurred simultaneously at around 8:30 to 8:50 a.m. on July 27, 2011, at the center of Seoul, Korea. This area is located in the southern part of Seoul and is a densely populated district. As a result of the debris flow event, 16 people were killed, 30 houses were buried, and 116 houses were damaged around Umyeon Mountain,
Chan-Young Yune, Yun-Ki Chae, Joongcheol Paik, Gihong Kim, Seung-Woo Lee, Heung-Seok Seo   +5 more
openaire   +1 more source