Results 71 to 80 of about 513,388 (355)

Experimental study on the impact load characteristics of a single-row pile dam against debris flow

Geomatics, Natural Hazards & Risk
A single-row pile dam is a type of rigid debris flow barrier structure. In order to reveal the mutual interaction effects between debris flow and a single-row pile dam and the distribution law of debris flow impact forces, an analysis of the correlation ...
Hao Sun, Zhuang Wang, Yong You, Wanyu Zhao, Jinfeng Liu, Dongwei Wang   +5 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Debris Flow Debris Flow Detection by Combinations of LVP Sensors and Wires: Examples in Sakura-jima Island in Japan

Journal of the Civil Engineering Forum
Various kinds of sensors for debris flows detection have been proposed such as wire sensor, acceleration sensor, and so on. In Europe, a geophone that is based on a vibration meter is usually used though the applicability is not confirmed for debris ...
Takahiro Itoh, Satoshi Tagata, Takahisa Mizuyama   +2 more
doaj   +1 more source

Morphological characteristics and conditions of drainage basins contributing to the formation of debris flow fans: an examination of regions with different rock strength using decision tree analysis [PDF]

Natural Hazards and Earth System Sciences
Debris flows cause severe disasters that can result in human casualties and the collapse of houses. The establishment of early warning systems in basins with high debris flow risks is needed to reduce the negative impacts of debris flow disasters ...
K. Koshimizu, S. Ishimaru, F. Imaizumi, G. Kawakami   +3 more
doaj   +1 more source

Simulasi Penanganan Potensi Aliran Debris di Gunung Sago (Studi Kasus di Batang Lakin, Kecamatan Lareh Sago Halaban, Kabupaten Lima Puluh Kota) [PDF]

, 2014
The regions in foothills of Sago mountain are flood-prone area due to debris flow. As occurred on March 22, 2010, there has been a catastrophic overflow of debris flow from Sago mountain.
Hadthya, R. \u27. (Reinhart), Sujatmoko, B. \u27. (Bambang), Sutikno, S. (Sigit)   +2 more
core  

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Differential analysis of sediment volume on fluid properties and debris flow disaster impact in the northwest traffic corridor of Sichuan Province

Zhongguo dizhi zaihai yu fangzhi xuebao
The LJ9 segment of Jiumian Expressway frequently experiences gully-type debris flow disasters, posing threats to nearby villages and infrastructure. Considering the unique characteristics and importance of the highway and G247 national road, this study ...
Ling LI, Ningsheng CHEN, Yi YANG, Zheng ZHONG, Na HUANG   +4 more
doaj   +1 more source

Dynamic Simulation and Analysis of Large-Scale Debris Flow Field

Geofluids, 2022
The method of two-phase flow is used to analyze the three-dimensional debris flow field via the theory of computational fluid dynamics (CFD). The theory of computational fluid dynamics and finite volume method is introduced briefly, and the rheological ...
Zongyuan Ma, Jianqiang Liu
doaj   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

Debris flow hazards due to land use change above source areas in torrent catchments. The case study of Les Arcs (Savoie, France) [PDF]

, 2009
For a few decades, land use has changed due to developments in mountainous regions and this has resulted in new pressures on the environment. Consequently, slope instabilities could be a physical expression of such imbalance.
Cojean, Roger, Koscielny, Mathilde, Thenevin, Isabelle   +2 more
core   +2 more sources