Results 51 to 60 of about 513,388 (355)

Experimental study on the impact of wide graded debris flow on check dam in high altitude area

open access: yesShuiwen dizhi gongcheng dizhi
The impact force of debris flow is the main cause of damage and destruction of check dam. In high altitude area, due to high mountains and deep valleys, serious physical weathering of surface materials, a wide range of source materials gradation, high ...
Shengqing HE, Da ZHENG, Wen ZHANG
doaj   +1 more source

Assessment and Analysis of a Rainfall–Time-Lagging Water-Related Disaster in Mountainous Areas

open access: yesFrontiers in Earth Science, 2021
Both global climate change and human activities are continuously impacting the abruptness and frequency of water-related natural disasters such as flash floods, debris flows, and landslides in mountainous areas, greatly threatening the safety of lives ...
Xu-Feng Yan   +5 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Analysis of debris flow control effect and hazard assessment in Xinqiao Gully, Wenchuan Ms 8.0 earthquake area based on numerical simulation

open access: yesChina Geology
: Xinqiao Gully is located in the area of the 2008 Wenchuan Ms 8.0 earthquake in Sichuan province, China. Based on the investigation of the 2023 “6-26” Xinqiao Gully debris flow event, this study assessed the effectiveness of the debris flow control ...
Chang Yang   +5 more
doaj   +1 more source

Analysis on disaster characteristics and prevention measures of the post-fire debris flow in Dianchichang gully, Xichang of Sichuan Province

open access: yesZhongguo dizhi zaihai yu fangzhi xuebao, 2022
Post-fire debris flow is a special torrent containing a large amount of loose material, which is closely related to forest fire. Its characteristics are significantly different from the conventional debris flow.
Xiangbin YANG   +6 more
doaj   +1 more source

RRS Charles Darwin Cruise 126, 11 Mar-20 Mar 2001. Piston coring of debris flows and turbidites west and south of the Canary Islands [PDF]

open access: yes, 2002
The major cruise objective was to obtain sediment cores at various locations to the west and southwest of the Canary Islands with the aims of :· Sampling debris flow sediments in the Canary and Saharan debris flows· Obtaining dateable sediments ...
Masson, D.G.
core  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Assessment of debris flow risk in Mentougou District, Beijing, based on runout of potential debris flow

open access: yesFrontiers in Earth Science
Debris flow is a prevalent geological disaster in Beijing, particularly in the Mentougou District, situated in the mountainous southwestern region of Beijing City. The past irrational exploitation of minerals has led to a substantial accumulation of slag,
Yongchao Li   +22 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

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