Results 51 to 60 of about 5,550,692 (265)

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

Debris Flow Assessment in the Gaizi-Bulunkou Section of Karakoram Highway

open access: yesFrontiers in Earth Science, 2021
Highways frequently run through the flow and accumulation areas of debris flow gullies and thus are susceptible to debris flow hazards. Assessing debris flows along highways can provide references for highway planners and debris flow control, emergency ...
Ning Jiang   +11 more
doaj   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

open access: yesFEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan   +11 more
wiley   +1 more source

The Controlling Actuality and Countermeasure of Debris Flow in Babuli Gully of Jinchuan County

open access: yesShuitu baochi yanjiu, 2006
Debris-flow hazards is one kind of mountain hazards.In our country,debris-flow brings great hazards to people who live in mountain regions.Babuli gully lies in outskirts of Jinchuan county which is an old debris-flow gully.To stop debris-flow hazards ...
ZHANG Gui-xiang~
doaj  

Debris Flow Susceptibility Mapping Using Machine-Learning Techniques in Shigatse Area, China

open access: yesRemote Sensing, 2019
Debris flows have been always a serious problem in the mountain areas. Research on the assessment of debris flows susceptibility (DFS) is useful for preventing and mitigating debris flow risks.
Yong-Hong Zhang   +3 more
semanticscholar   +1 more source

Debris flow susceptibility mapping using frequency ratio and seed cells, in a portion of a mountain international route, Dry Central Andes of Argentina

open access: yesCATENA, 2020
Debris flow and floods represent one of the main natural hazards that impact transport infrastructure, causing serious damage, economic losses and hinder regional economic development.
M. Y. Esper Angillieri
semanticscholar   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Assessment of debris flow risk in Mentougou District, Beijing, based on runout of potential debris flow

open access: yesFrontiers in Earth Science
Debris flow is a prevalent geological disaster in Beijing, particularly in the Mentougou District, situated in the mountainous southwestern region of Beijing City. The past irrational exploitation of minerals has led to a substantial accumulation of slag,
Yongchao Li   +22 more
doaj   +1 more source

A Case Study on the Closed-Type Barrier Effect on Debris Flows at Mt. Woomyeon, Korea in 2011 via a Numerical Approach

open access: yesEnergies, 2021
Debris flows are capable of flowing with high velocities and causing significant economic and infrastructural damage. As a hazard mitigation measure, physical barriers are frequently installed to dissipate the energy of debris flows.
Shin-Kyu Choi, Tae-Hyuk Kwon
doaj   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

open access: yesFEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph   +7 more
wiley   +1 more source

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