Results 41 to 50 of about 513,388 (355)

Direct Detection of Dark Matter Debris Flows

open access: yes, 2012
Tidal stripping of dark matter from subhalos falling into the Milky Way produces narrow, cold tidal streams as well as more spatially extended "debris flows" in the form of shells, sheets, and plumes. Here we focus on the debris flow in the Via Lactea II
David N. Spergel   +4 more
core   +1 more source

Numerical Modeling of Debris Flows Induced by Dam-Break Using the Smoothed Particle Hydrodynamics (SPH) Method [PDF]

open access: yes, 2020
Dam-break flows may change into debris flows if certain conditions are satisfied, such as abundant loose material and steep slope. These debris flows are typically characterized by high density and can generate strong impact forces. Due to the complexity
Qin, Jiping   +5 more
core   +3 more sources

Analysis of debris flow engineering treatment effect based on DEM data preprocessing in small watershed: A case study of Fangjiagou debris flow, Zhangxian County

open access: yesShuiwen dizhi gongcheng dizhi
After the Minxian-Zhangxian magnitude 6.6 earthquake on July 22, 2013, debris flow occurred in Fangjiagou, Zhangxian County. To reduce the potential damage of debris flow, a three-level check dam and drainage channel were built in the gully to regulate ...
Jingkai QU   +7 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

An Assessment Method for Debris Flow Dam Formation in Taiwan

open access: yesEarth Sciences Research Journal, 2018
Debris flows in tributaries rush into and block the main branches of rivers and often result in serious hazards. Dam failures cause large floods in the downstream area and can lead to fatalities and property damage.
Kun-Ting Chen   +5 more
doaj   +1 more source

Effects of closed immersion filtered water flow velocity on the ablation threshold of bisphenol A polycarbonate during excimer laser machining [PDF]

open access: yes, 2010
A closed flowing thick film filtered water immersion technique ensures a controlled geometry for both the optical interfaces of the flowing liquid film and allows repeatable control of flow-rate during machining.
Dowding, Colin   +2 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

A new data assimilation procedure to develop a debris flow run-out model [PDF]

open access: yes, 2015
Parameter calibration is one of the most problematic phases of numerical modeling since the choice of parameters affects the model\u2019s reliability as far as the physical problems being studied are concerned. In some cases, laboratory tests or physical
Bossi, G.   +5 more
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

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