Results 31 to 40 of about 3,373,389 (301)
Based on the coupled SPH-DEM-FEM numerical method, this paper analyzes the dynamic interaction of solid debris flow particle-liquid debris flow slurry-retaining dam in order to explore the dynamic response of retaining dam under the impact of the solid ...
Bailong Li +6 more
doaj +1 more source
Data was generated for 98 debris flow erosion experiments in a 5.4 m long flume with an erodible loosely packed sediment bed. In the 98 experiments the bed conditions were kept constant, but the composition of the debris flow changed.
Lonneke Roelofs (Utrecht University)
core +1 more source
The distribution of debris flows and debris flow hazards in southeast China [PDF]
Debris flows commonly occur throughout southern China, posing a hazard to people, property and infrastructure. Although debris flows occur more frequently and with greater magnitude in mountainous southwest China, where they have been studied extensively, their impacts on society are greater in southeast China, where population densities and land use ...
F. Wei +4 more
openaire +1 more source
Min County is an area with frequent debris flow in the south part of Gansu Province. In order to study the movement and accumulation characteristics of debris flow, the Malu River basin in Min County, Gansu Province, which was affected by serious debris ...
Peng CAO +6 more
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Debris-flow erosion and deposition dynamics [PDF]
Debris flows are a major natural hazard in mountains world wide, because of their destructive potential. Prediction of occurrence, magnitude and travel distance is still a scientific challenge, and thus research into the mechanics of debris flows is ...
SCHÜRCH, PETER
core
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Assessing the dynamic influences of slope angle and sediment composition on debris flow behaviour: An experimental approach [PDF]
Debris flows are hazards that can inflict significant infrastructural damage and loss of life. Their rapid and unpredictable onset in isolated locations means that field studies are limited.
FAIRFIELD, GEORGINA
core

