ITGB1 Regulates Triple‐Negative Breast Cancer Development by Modulating the Tumor Microenvironment
ABSTRACT Tumorigenesis and metastasis are frequently attributed to the intricate interplay between cancer cells and the tumor microenvironment (TME). Comprehending the mechanisms and key regulators of cancer‐immune crosstalk in the TME is imperative for developing efficacious immunotherapy.
Nuozi Song +12 more
wiley +1 more source
An integrated IKOA-CNN-BiGRU-Attention framework with SHAP explainability for high-precision debris flow hazard prediction in the Nujiang river basin, China. [PDF]
Yang H, Wang T, Fomin NI, Xiao S, Liu L.
europepmc +1 more source
Testing the use of OSL from quartz grains for dating debris flows in Miyun, northeast Beijing, China
Qiuyue Zhao +9 more
openalex +2 more sources
Endocytic Control of Cell‐Autonomous and Non‐Cell‐Autonomous Functions of p53
NUMB Ex3‐containing isoforms localize to the plasma membrane, where they recruit p53 through SNX9 and direct it to multivesicular bodies and exosomes. Exported p53 is taken up by neighboring cells and activates nuclear programs, revealing an intercellular, exosome‐based pathway that might help establish a tumor‐suppressive microenvironment.
Roberta Cacciatore +20 more
wiley +1 more source
Experimental Investigation of Uranium and Iron Condensation from High-Temperature Plasma Conditions. [PDF]
Weerakkody EN +6 more
europepmc +1 more source
TEAD1 Enhances Exosome Secretion and Promotes Exosome‐Mediated Tissue Regeneration
TEAD1 functions as a crucial molecular switch regulating exosome secretion in various cell types. TEAD1 enhances exosome secretion by upregulating key proteins associated with exosome secretion, including RAB11, CD9, and SNAP23. This study reveals a novel role for TEAD1 in regulating exosome secretion and tissue regeneration, particularly in diabetic ...
Yan Pu +9 more
wiley +1 more source
Deep learning-based debris flow hazard detection and recognition system: a case study. [PDF]
Wu F +4 more
europepmc +1 more source
This review provides a comprehensive exploration of microstructure regulation strategies for multi‐principal element alloy‐based films and coatings, with a focus on the interplay between elemental composition, nanoscale architecture, heterostructures and interfacial engineering in tailoring their properties and functions. A systematic analysis of their
Jiaming Cao +4 more
wiley +1 more source
Influence of path materials on rock avalanche dynamics in the Nayong case study. [PDF]
Zhang XS +5 more
europepmc +1 more source
This study presents a vascularized 3D tumor model to investigate immune–stromal–tumor interactions under allogeneic PBMC perfusion. While immune cells induced tumor shrinkage, they also promoted vascular regression, stromal activation, and cancer cell invasion.
Alexandra Raab +8 more
wiley +1 more source

