Blinatumomab is an immunotherapeutic agent with dual specificity for CD3 and CD19 that is approved for the treatment of relapsed/refractory B-cell precursor acute lymphoblastic leukemia (R/R B-ALL).
Massimiliano Bonifacio+10 more
doaj +2 more sources
We reviewed the literature (January 2010–June 2021) on the effectiveness of debulking strategies before venetoclax initiation in patients with chronic lymphocytic leukemia to reduce tumor burden, downgrade tumor lysis syndrome (TLS) risk, and avoid ...
Jeffrey P. Sharman+8 more
doaj +2 more sources
Microfluidic cell sorting: a review of the advances in the separation of cells from debulking to rare cell isolation. [PDF]
Accurate and high throughput cell sorting is a critical enabling technology in molecular and cellular biology, biotechnology, and medicine. While conventional methods can provide high efficiency sorting in short timescales, advances in microfluidics have
C. W. Shields+2 more
semanticscholar +2 more sources
SIMULTANEOUS DEBULKING OF GREAT OMENTUM LIKE A PALLIATIVE STAGE OF METABOLIC SYNDROM AND OBESITY TREATMENT = СИМУЛЬТАННИЙ ДЕБАЛКІНГ ЧЕПЦЯ ЯК ПАЛІАТИВНИЙ ЕТАП ЛІКУВАННЯ МЕТАБОЛІЧНОГО СИНДРОМУ І ОЖИРІННЯ [PDF]
Mylytsya К. M., Lavryk А. S., Lavryk О. А. SIMULTANEOUS DEBULKING OF GREAT OMENTUM LIKE A PALLIATIVE STAGE OF METABOLIC SYNDROM AND OBESITY TREATMENT = СИМУЛЬТАННИЙ ДЕБАЛКІНГ ЧЕПЦЯ ЯК ПАЛІАТИВНИЙ ЕТАП ЛІКУВАННЯ МЕТАБОЛІЧНОГО СИНДРОМУ І ОЖИРІННЯ. Journal
K. M. Mylytsya+2 more
doaj +2 more sources
Enlarged cardiophrenic lymph nodes predict disease involvement of the upper abdomen and the outcome of primary surgical debulking in advanced ovarian cancer [PDF]
The outcome of ovarian cancer patients is highly dependent on the success of primary debulking surgery in terms of postoperative residual disease.
A. Luger+6 more
semanticscholar +2 more sources
Clinical efficacy analysis of chemotherapy of isolated neck lymphatic metastasis in advanced epithelial ovarian cancer [PDF]
Objective The aim of this study was to retrospectively investigate the efficacy of chemotherapy for neck lymph node metastasis (NLNM) by determining the characteristics and survival of patients with isolated NLNMs metastases from epithelial ovarian ...
Hong Liu+6 more
doaj +2 more sources
A rationale for surgical debulking to improve anti-PD1 therapy outcome in non small cell lung cancer [PDF]
Anti-PD1 immunotherapy has emerged as a gold-standard treatment for first- or second-line treatment of stage IV NSCLC, with response rates ranging from 10 to 60%. Strategies to improve the disease control rate are needed.
F. Guisier+4 more
semanticscholar +2 more sources
Metabolic active peritoneal sites affect tumor debulking in ovarian and peritoneal cancers
Rationale and objectives To evaluate the impact of metabolic parameters in the peritoneal cavity on the likelihood of achieving complete tumor debulking in patients with ovarian and peritoneal cancers.
Tung Tung Tsoi+4 more
doaj +2 more sources
The role of quaternary cytoreduction in relapsed ovarian cancer – a systematic review [PDF]
Introduction. Ovarian cancer is characterized by a high capacity of relapse, even in cases in whom cytoreductive surgery with curative intent followed by platinum and taxanes-based chemotherapy were performed.
Nicolae BACALBASA+6 more
doaj +1 more source
Outcomes With Percutaneous Debulking of Tricuspid Valve Endocarditis
BACKGROUND: In patients with tricuspid valve infective endocarditis, percutaneous debulking is a treatment option. However, the outcomes of this approach are less well known.
Robert S. Zhang+9 more
semanticscholar +1 more source