Results 131 to 140 of about 59,353 (325)

Outcome of Liposuction for Limb Lymphedema in Men Compared with Women

open access: yesJournal of Plastic and Reconstructive Surgery
Objectives: Liposuction effectively reduces limb volume in cases of advanced fat-dominant lymphedema. This study compares surgical outcomes between men and women using Brorson's liposuction for lymphedema protocol. Methods: A total of 11 men and 11 women
Helen Mackie   +6 more
doaj  

Efficacy and safety of neoadjuvant chemotherapy versus primary debulking surgery in patients with ovarian cancer: a meta-analysis

open access: yesJournal of Gynecologic Oncology, 2019
Objective Neoadjuvant chemotherapy (NACT) for the treatment of epithelial ovarian cancer (EOC) has remained controversial. This meta-analysis was performed to systematically assess the efficacy and safety of NACT versus primary debulking surgery (PDS) in
Xiaofeng Lv   +3 more
semanticscholar   +1 more source

The role of blinatumomab in adult acute B lymphoblastic leukaemia

open access: yesBritish Journal of Haematology, EarlyView.
Blinatumomab, a CD19‐directed bispecific T‐cell engager, has become a crucial part of BCP‐ALL therapy in r/r disease, MRD‐positive disease and has recently been implemented into first‐line therapy of BCP‐ALL. This review discusses important clinical trials with a focus on blinatumomab in first‐line therapy of adult BCP‐ALL.
Anne C. Wilke, Nicola Gökbuget
wiley   +1 more source

In Situ Thermal Inspection of Automated Fiber Placement Operations for Tow and Ply Defect Detection [PDF]

open access: yes
The advent of Automated Fiber Placement (AFP) systems have aided the rapid manufacturing of composite aerospace structures. One of the challenges that AFP systems pose is the uniformity of the deposited prepreg tape layers, which complicates detection of
Cramer, K Elliott   +2 more
core   +1 more source

BRCA1 Promoter Methylation in Ovarian Cancer: Clinical Relevance and a Novel Diagnostic Approach Using Fragment Analysis

open access: yesCancer Science, EarlyView.
With the aim of clinical applications, we established a simplified evaluation method for BRCA1 methylation using fragment analysis, called BRCA1‐FAM. We confirmed that high‐grade serous ovarian cancer patients with BRCA1 methylation had poor prognosis.
Saki Tsuchimochi   +20 more
wiley   +1 more source

Modified posterior pelvic exenteration for advanced ovarian cancer: ten-year experience in 17 resectable cases [PDF]

open access: yesEinstein (São Paulo), 2008
Objective: To assess safety, efficacy and impact on survival of low anterior en bloc resection (modified posterior pelvic exenteration) as part of optimal debulking for primary advanced ovarian cancer.
Sergio Renato Pais Costa   +1 more
doaj  

Prospective Single-Arm Trial of Endovascular Mechanical Debulking as Initial Therapy in Patients With Acute and Subacute Lower Limb Ischemia: One-Year Outcomes

open access: yesJournal of Endovascular Therapy, 2019
Purpose: To report the results of a prospective, single-arm study to establish whether the initial treatment of acute or subacute limb ischemia (ALI and SLI, respectively) can be accomplished successfully using endovascular mechanical debulking of the ...
M. Bulvas   +3 more
semanticscholar   +1 more source

Intraperitoneal chemotherapy for peritoneal metastases : an expert opinion

open access: yes, 2020
Introduction: The rationale for intraperitoneal (IP) drug delivery for patients with peritoneal metastases (PM) is based on the pharmacokinetic advantage resulting from the peritoneal-plasma barrier, and on the potential to adequately treat small, poorly
Braet, Helena   +4 more
core   +1 more source

Sensitization of Non‐M3 Acute Myeloid Leukemia Blasts to All‐Trans Retinoic Acid by the LSD1 Inhibitor Tranylcypromine: TRANSATRA Phase I Study

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT The treatment of elderly, nonfit acute myeloid leukemia (AML)/MDS patients with relapsed/refractory (R/R) disease remains challenging. As histone demethylase LSD1 (KDM1A) is a rational therapeutic target in AML, we conducted a phase I trial (“rolling‐six design”) with the LSD1 inhibitor tranylcypromine (TCP, dose levels [DL] 20, 40, 60, 80 mg ...
Michael Kruszewski   +22 more
wiley   +1 more source

Minimal invasive fixation following with radiotherapy for radiosensitive unstable metastatic spine

open access: yesBiomedical Journal, 2022
Background: Minimally invasive surgery (MIS) has become a feasible option for patients with spinal metastasis, but the effectiveness of percutaneous pedicle screw fixation (PPSF) without decompression in patients with severe cord compression remains ...
Jia-En Chi   +6 more
doaj  

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