Results 91 to 100 of about 8,738 (313)

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

Social Stigma and Depression among Asymptomatic COVID-19 Carriers in Shanghai, China: The Mediating Role of Entrapment and Decadence. [PDF]

Int J Environ Res Public Health, 2022
Chen H, Chen Y, Zhang Y, Wang Z, Shi D, Liu J, Yang X, Xu L, Cai Y, Hu F.   +9 more
europepmc   +1 more source

Decadence and the Critique of Modernity

, 2019
Decadence and Literature explains how the concept of decadence developed since Roman times into a major cultural trope with broad explanatory power. No longer just a term of opprobrium for mannered art or immoral behaviour, decadence today describes ...
Jane Desmarais, Desmarais, Jane H.
core   +1 more source

The Cosmic Extension of Fin: Aesthetics of Perceptual, Reflexive and Sensual Temporality in Nabokov’s Ada

Humanities
Fin-de-siècle decadence—marked by symbolism, dandyism, aesthetic withdrawal, and defiance of bourgeois norms—has long been reimagined beyond its original European contours.
Juan Wu
doaj   +1 more source

From Exquisite to Transgressive Moderns? The Goncourt's "Decadent" Eighteenth-Century Art Revival

Nordlit: Tidsskrift i litteratur og kultur, 2012
As avid collectors of French eighteenth-century art, the Goncourts' contribution to its nineteenth-century history is well-known. This article, however, explores a less welldocumented aspect of their L'Art du dix-huitième siècle (1858-1875): that is, its
Juliet Simpson
doaj   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

FROM DECADENCE TO TEURGY (CONNECTIONS IN GENESIS OF CZECH AND RUSSIAN LITERATURE AT THE END OF 19TH AND BEGINNING OF 20TH CENTURY)

Филологический класс, 2019
The article focuses on comparative analysis of aesthetic philosophical concepts of Czech and Russian symbolism at the end of 19th and the beginning of 20th century. The attention is predominantly paid to interpretation of selected theoretical studies and
doaj   +1 more source

Decadentes e modernidade // The decadents and modernity [PDF]

Svět Literatury, 2017
The paper explores definitions of modernity, with a particular focus on the relationship between Baudelaire’s modern poetry and the Portuguese poetry of Decadentismo.
Ernesto Rodrigues
doaj  

Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone, Freddy Chafota, Miguel E. Rentería, Randi J. Hagerman, Ellery Santos, Anna Atkinson, Nicholas G. Martin, Elsdon Storey, Danuta Z. Loesch   +8 more
wiley   +1 more source

Editor’s Foreword: ‘Decadence’ [PDF]

, 2019
Editor's Foreword to 'Decadence' (Moveable Type, Volume XI)
Zubair, S-J
core