The Early Regenerative Events in the Human Tympanic Membrane After In Vivo Traumatization
At 20 h after in vivo traumatization a regenerative response in the human tympanic membrane is activated. The results show an upregulated proliferation activity in the UPT in early healing and confirm the previously described regenerative regions of the annulus and malleus.
Elnaz Sepehri +5 more
wiley +1 more source
Rapid Postmortem Temporal Bone Extraction and Dissection of Human Inner Ear Organs From Organ Donors
We developed a postmortem protocol for temporal bone extraction and dissection in organ donors, enabling atraumatic bilateral temporal bone retrieval within 1–2 h of ischemia, followed by stepwise microsurgical dissection of neurosensory organs. Combining rapid extraction, abbreviated decalcification, and atraumatic microsurgical dissection, this ...
Yassine Balhi +10 more
wiley +1 more source
Schematic overview of the in vitro and in vivo evaluation of purpurin in promoting MK maturation and platelet production, through ESR1/PI3K/AKT. ABSTRACT Chemotherapy‐induced thrombocytopenia (CIT) increases bleeding risk and compromises chemotherapy delivery.
Xiaolin Gan +12 more
wiley +1 more source
Engineering an Enzymatically Active Granular Matrix for On‐Chip Modeling of Bone‐Like Mineralization
Alkaline phosphatase (ALP)‐functionalized poly(ethylene glycol) (PEG) microgels assemble into a perfusable granular matrix for cell‐free modeling of bone‐like mineralization. Microgel‐associated enzymatic activity promotes calcium phosphate deposition, producing a calcium‐deficient, poorly crystalline apatite‐like phase, while keeping interparticle ...
Farhad Sanaei +6 more
wiley +1 more source
Managing mitral annular calcification-high-end robotic mitral valve repair for experienced surgeons. [PDF]
Bonatti J, Kobayashi K.
europepmc +1 more source
Abstract Ground granulated blast‐furnace slag (GGBS) is a widely used clinker substitute in concrete, recognized for its potential to significantly reduce environmental impacts. However, its application in prestressed concrete remains limited in several countries, mainly due to concerns regarding early‐age mechanical performance and long‐term ...
D. Rolando Baldiviezo +6 more
wiley +1 more source
Advances in deep‐tissue fluorescence imaging through optical clearing: A review
Optical clearing refers to techniques that are used to improve the optical transparency of biological tissues. Optical clearing enables imaging of deeper lying tissues as well as 3D volumetric imaging of whole organs. This review examines reports on the integration of optical clearing with advanced fluorescence imaging techniques, with particular ...
Alaka Pramod +4 more
wiley +1 more source
Mechanism of Mechanical Activation-Assisted Selective Decalcification of Vanadium-Bearing Steel Slag. [PDF]
Zhang M +5 more
europepmc +1 more source
Magnetothermal‐responsive drug release bone cement based on EGFR‐mutated lung cancer bone metastases
A novel magnetothermal‐responsive bone cement was developed by integrating PMMA/CPC/Osimertinib matrix with Fe3O4@SiO2@Zol nanomaterials. This dual‐drug system achieves controlled release, combining excellent mechanical properties with potent anti‐tumor activity and bone regulation for treating EGFR‐mutated LC‐BoM.
Kandi Xu +15 more
wiley +1 more source
Optimizing osteochondral decalcification and histological processing in ovine joint models. [PDF]
Faraldo NC +7 more
europepmc +1 more source

