Results 21 to 30 of about 2,171 (182)

Mechanical influences on morphogenesis of the knee joint revealed through morphological, molecular and computational analysis of immobilised embryos. [PDF]

open access: yesPLoS ONE, 2011
Very little is known about the regulation of morphogenesis in synovial joints. Mechanical forces generated from muscle contractions are required for normal development of several aspects of normal skeletogenesis.
Karen A Roddy   +2 more
doaj   +1 more source

DECAMETHONIUM AND HEXAMETHONIUM

open access: bronzeBritish Journal of Anaesthesia, 1950
A.R. Hunter
openaire   +2 more sources

Neuromuscular Blocking Agents and Cancer: A Narrative Review

open access: yesJournal of Clinical Pharmacy and Therapeutics, Volume 2023, Issue 1, 2023., 2023
Objective. Neuromuscular blocking agents (NMBAs) are part of the three elements of general anaesthesia (sedation, analgesia, and muscle relaxation), which can relax muscles and facilitate intubation and surgery. It has been reported that cancer cells are prone to invasion or metastasis during surgery, but various anaesthetics are currently used in ...
Rui Chen   +7 more
wiley   +1 more source

Quantifying the tolerance of chick hip joint development to temporary paralysis and the potential for recovery

open access: yesDevelopmental Dynamics, Volume 250, Issue 3, Page 450-464, March 2021., 2021
ABSTRACT Background Abnormal fetal movements are implicated in joint pathologies such as arthrogryposis and developmental dysplasia of the hip (DDH). Experimentally induced paralysis disrupts joint cavitation and morphogenesis leading to postnatal abnormalities.
Devi L. Bridglal   +3 more
wiley   +1 more source

Rates and equilibria at the acetylcholine receptor of electrophorus electroplaques. A study of neurally evoked postsynaptic currents and of voltage-jump relaxations [PDF]

open access: yes, 1977
Kinetic measurements are employed to reconstruct the steady-state activation of acetylcholine [Ach] receptor channels in electrophorus electroplaques. Neurally evoked postsynaptic currents (PSCs) decay exponentially; at 15°C the rate constant, α, equals ...
Lester, Henry A., Sheridan, Robert E.
core   +7 more sources

Enhanced activity of multiple TRIC-B channels: an endoplasmic reticulum/sarcoplasmic reticulum mechanism to boost counterion currents. [PDF]

open access: yesJ Physiol, 2019
Key points There are two subtypes of trimeric intracellular cation (TRIC) channels but their distinct single‐channel properties and physiological regulation have not been characterized. We examined the differences in function between native skeletal muscle sarcoplasmic reticulum (SR) K+‐channels from wild‐type (WT) mice (where TRIC‐A is the principal ...
O'Brien F   +8 more
europepmc   +2 more sources

GABA\u3csub\u3eA\u3c/sub\u3e and excitatory amino acid receptors in dorsomedial hypothalamus and heart rate in rats [PDF]

open access: yes, 1991
We have previously shown that microinjection of drugs that interfere with the function of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) into the hypothalamus produces cardiorespiratory and behavioral changes resembling those seen in ...
DiMicco, Joseph A., Soltis, Robert P.
core   +2 more sources

Light-Activated Pharmacological Tools for Exploring the Cholinergic System. [PDF]

open access: yesMed Res Rev
ABSTRACT Cholinergic transmission plays a critical role in both the central and peripheral nervous systems, affecting processes such as learning, memory, and inflammation. Conventional cholinergic drugs generally suffer from poor selectivity and temporal precision, leading to undesired effects and limited therapeutic efficacy. Photopharmacology aims to
Colleoni A   +5 more
europepmc   +2 more sources

The role of embryo movement in the development of the furcula [PDF]

open access: yes, 2017
The pectoral girdle is a complex structure which varies in its morphology between species. A major component in birds is the furcula, which can be considered equivalent to a fusion of the paired clavicles found in many mammals, and the single ...
Allen   +28 more
core   +2 more sources

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