A covalently bound photoisomerizable agonist. Comparison with reversibly bound agonists at electrophorus electroplaques [PDF]
After disulphide bonds are reduced with dithiothreitol, trans-3-(alpha-bromomethyl)-3’-[alpha-(trimethylammonium)methyl]azobenzene (trans-QBr) alkylates a sulfhydryl group on receptors.
Erlanger, Bernard F. +4 more
core +2 more sources
Synthesis and structural characterization of Zn-containing DAF-1 [PDF]
A study exploring the use of ionic liquid reactions based on imidazolium halides in molecular sieve synthesis has produced a novel zincoaluminophosphate material with an open DFO-type framework structure.
Baerlocher, Christian +6 more
core +1 more source
Sarcoplasmic Reticulum K+ (TRIC) Channel Does Not Carry Essential Countercurrent during Ca2+ Release [PDF]
The charge translocation associated with sarcoplasmic reticulum (SR) Ca2+ efflux is compensated for by a simultaneous SR K+ influx. This influx is essential because, with no countercurrent, the SR membrane potential (Vm) would quickly (
Guo, Tao +7 more
core +1 more source
Decamethonium Iodide (Bistrimethyl Ammonium Decane Diodide) in Anaesthesia [PDF]
Geoffrey Organe
openaire +3 more sources
Histochemical demonstration of three types of muscle fibers of the intercostal muscles. A study on oxidative enzymes [PDF]
Since the classic work of Ranvier, it is well known that the mammalian striated muscle is composed of two types of muscle fibers, i. e., the red and white muscle fibers.
Kawashima, Takao +2 more
core +1 more source
Histochemical studies on the red, white and intermediate muscle fibers of some skeletal muscles. Ⅲ. Histochemical demonstration of oxidative enzymes, phosphorylase and glycogen in respiratory muscle fibers [PDF]
1) Three different types of muscle fibers were clearly distinguished in the intercostal muscles and the diaphragm of human, cat and rat by histochemical demonstration of oxidative enzymes, phosphorylase and glycogen.
Nishiyama, Akira
core +1 more source
摘出ラット上頸交感神経節を用いて,刺激頻度と薬物作用との関係を検討し,次の結果を得た。1.Hexamethonium,d-Tubocurarine,PhysostigmineおよびParaoxon作用下では,神経節伝達抑制作用が低頻度刺激よりも高頻度刺激により増強された。このような薬物効果をType Aとした。2.Adrenaline(Adr.),Nor-Adrenaline(Nor-Adr),MgCl_2,MnCl_2ならびにCa^-deficit Ringer(0.1〜0.4mM CaCl_2)では,
Conrad Helm (187213) +3 more
core +4 more sources
Tonic and bursting activity in the cuneate nucleus of the chloralose-anesthetized cat [PDF]
[Abstract] Whole-cell recordings were obtained from cuneate neurons in anesthetized, paralysed cats. Stimulation of the contralateral medial lemniscus permitted us to separate projection cells from presumed interneurons.
Canedo Lamas, Antonio +2 more
core +2 more sources
In this study, we have employed in silico methodology combining double pharmacophore based screening, molecular docking, and ADME/T filtering to identify dual binding site acetylcholinesterase inhibitors that can preferentially inhibit acetylcholinesterase and simultaneously inhibit the butyrylcholinesterase also but in the lesser extent than ...
Shikhar Gupta +2 more
wiley +1 more source
Multinuclear Solid-State Magnetic Resonance as a Sensitive Probe of Structural Changes upon the Occurrence of Halogen Bonding in Co-crystals [PDF]
Although the understanding of intermolecular interactions, such as hydrogen bonding, is relatively well-developed, many additional weak interactions work both in tandem and competitively to stabilize a given crystal structure.
Cory M. Widdifield +7 more
core +1 more source

