Results 41 to 50 of about 326,648 (267)

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Automated Shoulder Girdle Rigidity Assessment in Parkinson’s Disease via an Integrated Model- and Data-Driven Approach

open access: yesSensors
Parkinson’s disease (PD) is characterized by motor symptoms, with key diagnostic features, such as rigidity, traditionally assessed through subjective clinical scales.
Fatemeh Khosrobeygi   +6 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

General Decay of Solutions for a Coupled System of Kirchhoff-Carrier-Type Viscoelastic Wave Equations with Balakrishnan-Taylor Damping [PDF]

open access: yesSahand Communications in Mathematical Analysis
This paper examines a coupled system of Kirchhoff-Carrier-type viscoelastic wave equations with Balarkrishnan-Taylor damping. The local existence and uniqueness of solutions for the given problem are proved by utilizing the Faedo-Galerkin method and ...
Bui Nam   +4 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Extraction of Model Parameters for Reactive Solute Transport [PDF]

open access: yesJournal of Rehabilitation in Civil Engineering, 2019
Rock material is common in the construction of hydraulic structures. In the present study, to the aim is to examine the reactive solute relationships for transport and degradation processes through the rockfill media.
Jafar Chabokpour, Ali Akhoundzadeh
doaj   +1 more source

The Application of PMA (Propidium Monoazide) to Different Target Sequence Lengths of Zebrafish eDNA: A New Approach Aimed Toward Improving Environmental DNA Ecology and Biological Surveillance

open access: yesFrontiers in Ecology and Evolution, 2021
Environmental DNA (eDNA) analysis has enabled more sensitive and efficient biological monitoring than traditional methods. However, since the target species is not directly observed, interpretation of results cannot preclude process Type I errors ...
Takaya Hirohara   +5 more
doaj   +1 more source

Spontaneous decay rates in active waveguides [PDF]

open access: yesOptics Letters, 2005
We present a new method to measure the guided, radiated and total decay rates in one-dimensional waveguides. It is also theoretically shown that large modifications of the total decay rate can be achieved in realistic EDFAs and EDWAs with effective mode area radii smaller than ~ 1 micrometer.
Rieznik, A. A., Rigolin, G.
openaire   +3 more sources

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