Results 101 to 110 of about 13,447,510 (348)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Qualitative properties of solutions to a generalized Fisher–KPP equation

open access: yesElectronic Journal of Qualitative Theory of Differential Equations
The following Fisher–KPP type equation $$ u_t=Ku_{xx}-Bu^q+Au^p, \quad (x,t)\in\mathbb{R}\times(0,\infty), $$ with $p>q>0$ and $A$, $B$, $K$ positive coefficients, is considered.
Razvan Gabriel Iagar, Ariel Sánchez
doaj   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

decay rate

open access: yes, 2010
Citation: 'decay rate' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.D01542 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

On the interpretation of annual oscillations in 32Si and 36Cl decay rate measurements

open access: yesScientific Reports, 2021
The 32Si decay rate measurement data of Alburger et al. obtained in 1982–1986 at Brookhaven National Laboratory have been presented repeatedly as evidence for solar neutrino-induced beta decay.
S. Pommé   +3 more
doaj   +1 more source

How to decay your learning rate

open access: yesCoRR, 2021
Complex learning rate schedules have become an integral part of deep learning. We find empirically that common fine-tuned schedules decay the learning rate after the weight norm bounces. This leads to the proposal of ABEL: an automatic scheduler which decays the learning rate by keeping track of the weight norm. ABEL's performance matches that of tuned
openaire   +2 more sources

Negative modes and the decay-rate transition [PDF]

open access: yesPhysical Review B, 1999
We investigate a relationship between the number of the negative modes around periodic instanton solution and the type of the decay-rate transition. It is shown that for the case of first-order decay-rate transition the lowest positive mode at low energy periodic instanton becomes additional negative mode at high energy regime, while in the second ...
Lee, Soo-Young   +3 more
openaire   +2 more sources

On analyticity and temporal decay rates of solutions to the viscous resistive Hall-MHD system [PDF]

open access: yes, 2014
We address the analyticity and large time decay rates for strong solutions of the Hall-MHD equations. By Gevrey estimates, we show that the strong solution with small initial date in H r ( R 3 ) with r > 5 2 becomes analytic immediately after t > 0 , and
S. Weng
semanticscholar   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito   +14 more
wiley   +1 more source

Home - About - Disclaimer - Privacy