Results 121 to 130 of about 13,447,510 (348)
RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers +7 more
wiley +1 more source
Mass corrections to the tau decay rate
In this note radiative corrections to the total hadronic decay rate of the $τ$-lepton are studied employing perturbative QCD and the operator product expansion. We calculate quadratic quark mass corrections to the decay rate ration $R_τ$ to the order ${\cal O}(α_s^2 m^2)$ and find that they contribute appreciably to the Cabbibo supressed decay modes of
Chetyrkin, Konstantin, Kwiatkowski, Axel
openaire +2 more sources
Objective Hydroxychloroquine (HCQ) is a cornerstone therapy in systemic lupus erythematosus (SLE), but the weight‐based dosing does not account for clinical factors that can introduce individual variability in drug metabolism and clearance. We leveraged longitudinal data from a prospective SLE cohort to identify clinical factors that predict ...
Jay J. Patel +6 more
wiley +1 more source
We consider the time decay rates of smooth solutions to the Cauchy problem for the compressible Navier-Stokes system with and without a Yukawa-type potential.
Qing Chen +3 more
doaj
A Q‐Learning Algorithm to Solve the Two‐Player Zero‐Sum Game Problem for Nonlinear Systems
A Q‐learning algorithm to solve the two‐player zero‐sum game problem for nonlinear systems. ABSTRACT This paper deals with the two‐player zero‐sum game problem, which is a bounded L2$$ {L}_2 $$‐gain robust control problem. Finding an analytical solution to the complex Hamilton‐Jacobi‐Issacs (HJI) equation is a challenging task.
Afreen Islam +2 more
wiley +1 more source
This article proposes a convergent adaptive observer for a damped wave PDE and an infinite‐dimensional ODE coupled in cascade using sampled‐in‐space ODE state measurements. The proposed observer estimates the distributed states of the PDE and ODE along with unknown PDE parameters and spatial input.
Zehor Belkhatir +2 more
wiley +1 more source
Excited State Structure and Decay Rates for Aggregates
Electronic excited state in molecular aggregate or exciton states continue to attract great attention due to the increasing demands for applications of molecular optoelectronics and sensing technology.
Zhigang Shuai +4 more
doaj +1 more source
On the excitation and radiative decay rates of plasmonic nanoantennas. [PDF]
Bedingfield K, Demetriadou A.
europepmc +1 more source
The stability criteria affecting the formation of high‐entropy alloys, particularly focusing in supersaturated solid solutions produced by mechanical alloying, are analyzed. Criteria based on Hume–Rothery rules are distinguished from those derived from thermodynamic relations. The formers are generally applicable to mechanically alloyed samples.
Javier S. Blázquez +5 more
wiley +1 more source

