Results 211 to 220 of about 11,220 (243)

The Progress of Decellularized Scaffold in Stomatology

Tissue Engineering and Regenerative Medicine, 2022
The oral and maxillofacial region contains oral organs and facial soft tissues. Due to the complexity of the structures and functions of this region, the repair of related defects is complicated. Different degrees of defects require different repair methods, which involve a great combination of medicine and art, and the material requirements are ...
Ailin, Zeng, Huiru, Li, Jianguo, Liu, Mingsong, Wu   +3 more
openaire   +2 more sources

Decellularized human valve allografts

The Annals of Thoracic Surgery, 2001
Variable performance of allograft tissues in children and some adults may be linked to an immune response and could be mitigated by reducing implant antigenicity.As endothelial and fibroblast cells are the likely source of valve antigenicity, human (CryoValve SG) and sheep pulmonary valves were decellularized using the SynerGraft treatment process ...
R C, Elkins, P E, Dawson, S, Goldstein, S P, Walsh, K S, Black   +4 more
openaire   +2 more sources

Decellularized matrices in regenerative medicine

Acta Biomaterialia, 2018
Of all biologic matrices, decellularized extracellular matrix (dECM) has emerged as a promising tool used either alone or when combined with other biologics in the fields of tissue engineering or regenerative medicine - both preclinically and clinically.
Doris A, Taylor, Luiz C, Sampaio, Zannatul, Ferdous, Andrea S, Gobin, Lakeshia J, Taite   +4 more
openaire   +2 more sources

Decellularized vs Non-decellularized Allogeneic Pulmonary Artery Patches for Pulmonary Arterioplasty

Seminars in Thoracic and Cardiovascular Surgery, 2023
We studied pulmonary artery size, reinterventions, and panel reactive antibodies in patients with single-ventricle physiology who underwent a pulmonary arterioplasty with decellularized (DAPAP) and non-decellularized allogeneic pulmonary artery patches (non-DAPAP).
Carlos Bonilla-Ramirez, Varun Aggarwal, Manasa Atyam, Athar M. Qureshi, Jeffrey S. Heinle, E. Dean McKenzie   +5 more
openaire   +2 more sources

Tracheal Cartilage Isolation and Decellularization

2017
Tissue decellularization allows isolation of tissue extracellular matrix components, enabling bioengineering of native tissue microenvironments with minimal antigenic components. Here we describe a method to harvest decellularized cartilage tissue from donor trachea using a series of chemical and enzymatic washes and incorporating the extracellular ...
Zachary, Galliger, Angela, Panoskaltsis-Mortari   +1 more
openaire   +2 more sources

Perfusion decellularization of whole organs

Nature Protocols, 2014
The native extracellular matrix (ECM) outlines the architecture of organs and tissues. It provides a unique niche of composition and form, which serves as a foundational scaffold that supports organ-specific cell types and enables normal organ function.
Jacques P, Guyette, Sarah E, Gilpin, Jonathan M, Charest, Luis F, Tapias, Xi, Ren, Harald C, Ott   +5 more
openaire   +2 more sources

Decellularization of Liver and Organogenesis in Rats

2017
Recently, organ construction has been attempted using decellularized organs. In this study, we used decellularized rat liver to construct liver tissue by recellularization. The right lobe of the rat liver was decellularized with 4% Triton X-100 solution, recellularized with 107 rat hepatocytes, and albumin synthesis in the recellularized right lobe was
Nana, Shirakigawa, Hiroyuki, Ijima
openaire   +2 more sources

Decellularized matrices for tissue engineering

Expert Opinion on Biological Therapy, 2010
Biomimetic scaffolds and substrates of extracellular matrices (ECMs) play an important role in the regulation of cell function and in the guidance of new tissue regeneration, as an ECM has the intrinsic cues necessary to communicate with and dictate to cells.This paper reviews the latest developments in ECM scaffolds and substrates obtained from ...
Takashi, Hoshiba, Hongxu, Lu, Naoki, Kawazoe, Guoping, Chen   +3 more
openaire   +2 more sources

Decellularization for whole organ bioengineering

Biomedical Materials, 2013
Organ transplantation in an orthotopic location is the current treatment for end-stage organ failure. However, the need for transplantable organs far exceeds the number of available donor organs. As a result, new options, such as tissue engineering and regenerative medicine, have been explored to achieve functional organ replacement.
J E, Arenas-Herrera, I K, Ko, A, Atala, J J, Yoo   +3 more
openaire   +2 more sources

Corneal extracellular matrix decellularization

2020
Decellularized corneal scaffolds have the potential to be used as alternatives to donor corneas during keratoplasty. Here a decellularization technique is described that involves the use of sodium dodecyl sulfate, Triton-X100, DNAse and RNAse to remove cells and cellular constituents.
openaire   +2 more sources