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Decellularization for whole organ bioengineering
Biomedical Materials, 2013Organ transplantation in an orthotopic location is the current treatment for end-stage organ failure. However, the need for transplantable organs far exceeds the number of available donor organs. As a result, new options, such as tissue engineering and regenerative medicine, have been explored to achieve functional organ replacement.
J E, Arenas-Herrera +3 more
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Decellularization of tissues and organs
Biomaterials, 2006Decellularized tissues and organs have been successfully used in a variety of tissue engineering/regenerative medicine applications, and the decellularization methods used vary as widely as the tissues and organs of interest. The efficiency of cell removal from a tissue is dependent on the origin of the tissue and the specific physical, chemical, and ...
Thomas W, Gilbert +2 more
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Decellularization and Recellularization of Cartilage
2017Decellularization of cartilage enables the use of cartilage allografts or xenografts as natural scaffolds for repair and regeneration of injured cartilage. The preservation of the extracellular matrix ultrastructure of the graft makes this a promising tool for cartilage tissue engineering.
Catherine A, Bautista, Bahar, Bilgen
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Decellularized Tissue Engineering
2017Tissue Engineering consists of cells, a scaffold and cytokines. Decellularization represents the removal of cells from tissues or organs. Recently, decellularized tissue has been investigated as a scaffold for tissue engineering, termed decellularized tissue engineering.
Nana Shirakigawa, Hiroyuki Ijima
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Decellularized matrices for tissue engineering
Expert Opinion on Biological Therapy, 2010Biomimetic scaffolds and substrates of extracellular matrices (ECMs) play an important role in the regulation of cell function and in the guidance of new tissue regeneration, as an ECM has the intrinsic cues necessary to communicate with and dictate to cells.This paper reviews the latest developments in ECM scaffolds and substrates obtained from ...
Takashi, Hoshiba +3 more
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Journal of Bioscience and Bioengineering, 2016
As the endoscopic technique is widely used in the diagnosis and treatment of diseases, the incidence of ureteral injuries increases annually. The classical surgical therapies are not always satisfactory. With the constant development of the tissue engineering technology in the field of urinary reconstruction, the ureteral reconstruction has become ...
Shu-Wei, Xiao +5 more
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As the endoscopic technique is widely used in the diagnosis and treatment of diseases, the incidence of ureteral injuries increases annually. The classical surgical therapies are not always satisfactory. With the constant development of the tissue engineering technology in the field of urinary reconstruction, the ureteral reconstruction has become ...
Shu-Wei, Xiao +5 more
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Decellularization Methods for Scaffold Fabrication
2017Decellularization is the process of removal of native cells from tissue, leaving behind a three-dimensional (3D) ultrastructure of extracellular matrix (ECM) proteins while preserving the bioactivity and mechanics of the tissue. It offers a unique top-down approach for fabricating ECM based natural scaffold for tissue engineering application.
Sweta K, Gupta +2 more
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Decellularization Concept in Regenerative Medicine
2019Decellularized organs and tissues are effectively utilized in a diversity of regenerative medicine purposes, and the decellularization approaches employed differ as broadly as the tissues/organs of concern. Biological scaffold substances formed by extracellular matrix (ECM) are mostly produced with methods that include decellularization of tissues ...
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