Results 121 to 130 of about 7,198 (311)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Decidability, Introduction Rules and Automata [PDF]

open access: yes, 2015
International audienceWe present a method to prove the decidability of provability in several well-known inference systems. This method generalizes both cut-elimination and the construction of an automaton recognizing the provable ...
Dowek, Gilles   +3 more
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Decidability problems in grammar systems

open access: yes, 1999
Most of the basic decision problems concerning derivations in cooperating distributed grammar systems have so far been open, possibly because of the lack of unifying methods and techniques. In this paper such a unifying device is proposed. It is called a
Mihalache, Valeria
core   +1 more source

Algorithmic Problems for Computation Trees

open access: yesLogics
In this paper, we study three algorithmic problems involving computation trees: the optimization, solvability, and satisfiability problems. The solvability problem is concerned with recognizing computation trees that solve problems.
Mikhail Moshkov
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Decidability of Split Equivalence

open access: yes, 1998
We show that the following problem is decidable: given expressions E 1 and E 2 constructed from variables by the regular operations and shu#e, is the identity E 1 = E 2 true for all instantiations of its variables by strings?
Y. Abramson, A. Rabinovich
core  

Decidability of Weak Bisimilarity for a Subset of BPA

open access: yes, 2008
In this paper we use the tableau as a means to prove decidability of weak bisimulation for normed BPA. Decidability was proved for a restricted subclass, the totally normed processes by Hirshfeld [Hirshfeld, Y., Bisimulation trees and the decidability of
Chen, Haiyan, Haiyan Chen
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Bisimulation Quantified Modal Logics: Decidability

open access: yes, 2008
. Bisimulation quantifiers are a natural extension of modal logics. They preserve the bisimulation invariance of modal logic, while allowing monadic second-order expressivity.
Tim French
core  

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