Results 11 to 20 of about 18,499 (206)

T-bet Fate Mapping Reveals Gestational Stage-Specific Transcriptional Adaptation of Decidual NK Cells. [PDF]

open access: yesAm J Reprod Immunol
ABSTRACT Problem Natural killer (NK) cells are critical regulators of immune balance at the maternal–fetal interface. T‐bet (Tbx21) is a key transcription factor shaping NK cell effector functions, yet its role in decidual NK (dNK) cell adaptation across gestation remains unclear.
Mohamed MA   +6 more
europepmc   +2 more sources

Treg cells retain stable lineage commitment during pregnancy in mice after late gestation inflammatory challenge. [PDF]

open access: yesImmunol Cell Biol
In this study, we used Foxp3‐fatemapping mice to examine the cell lineage stability of Treg cells in pregnancy. Ex‐Foxp3 cells were identified in gestational tissues. However, Treg cells retained lineage stability with no increased ex‐Foxp3 generation, regardless of inflammatory challenges that induce preterm birth.
Foyle KL   +6 more
europepmc   +2 more sources

Progesterone decreased indoleamine 2,3-dioxygenase 1(IDO1) expression in early pregnancy chorionic villi and decidua

open access: yesAutoimmunity, 2021
Indoleamine 2,3-dioxygenase1(IDO1) is one of the most important proteins in protect the embryos from the mother's immune system during pregnancy. However, the regulation of the protein expression at the maternal–foetal interface is not fully known.
Minyan Yang   +6 more
doaj   +1 more source

Ectopic decidua of the greater omentum: a case report

open access: yesJournal of Health Sciences, 2016
Ectopic decidua is defined as extrauterine deposits of decidual stromal cells. It occurs in 85-100% of pregnancies. Focal sites can be present in various locations, yet a peritoneal location is rare.
Biserka Pigac, Silvija Masic
doaj   +1 more source

CCL2: An important cytokine in normal and pathological pregnancies: A review

open access: yesFrontiers in Immunology, 2023
C-C motif ligand 2 (CCL2), also known as monocytic chemotactic protein 1 (MCP-1), is an integral chemotactic factor which recruits macrophages for the immune response.
Zhi Lin   +10 more
doaj   +1 more source

Innate Lymphoid Cells in the Maternal and Fetal Compartments

open access: yesFrontiers in Immunology, 2018
Pregnancy success is orchestrated by the complex balance between the maternal and fetal immune systems. Herein, we summarize the potential role of innate lymphoid cells (ILCs) in the maternal and fetal compartments.
Derek Miller   +12 more
doaj   +1 more source

MAIT Cells at the Fetal-Maternal Interface During Pregnancy

open access: yesFrontiers in Immunology, 2020
One of the main functions of the human placenta is to provide a barrier between the fetal and maternal blood circulations, where gas exchange and transfer of nutrients to the developing fetus take place.
Helen Kaipe   +7 more
doaj   +1 more source

Ectopic decidua

open access: yesActa clinica Croatica, 2007
Ectopic decidua is described as a physiological phenomen of a pregnancy, which is a result of subserous stromal cell metaplasia due to progesteron activity.
Pigac, B.   +4 more
  +7 more sources

Periodontal diseases and adverse pregnancy outcomes. Present and future

open access: yesPeriodontology 2000, EarlyView., 2023
Abstract For more than two decades the possible association between periodontal diseases and adverse pregnancy outcomes has been extensively evaluated. Numerous observational, intervention, and mechanistic studies have offered valuable information on this topic.
Yiorgos A. Bobetsis   +3 more
wiley   +1 more source

Uterine Natural Killer Cells and Implantation

open access: yesFertility & Reproduction, 2021
Decidual leukocytes make up approximately 30% of all decidual stromal cells in early pregnancy, of which 70% are uterine natural killer (uNK) cells. uNK cells are phenotypically distinct from peripheral blood NK cells, being CD56brightCD16−.
Gendie E. Lash
doaj   +1 more source

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