Results 121 to 130 of about 2,930,584 (242)
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Problemas tipo en teoría de la decisión [PDF]
, 1997 El objetivo de este artículo es ilustrar las técnicas y los conceptos básicos de la Teoría de la Decisión. Para lograr este objetivo se ha adoptado el problema tipo quizá más sencillo: el problema de la inversión.
Alonso Sanz, Ramón
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Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
El mínimo argumental de la decisión judicial [PDF]
, 2019 El mínimo argumental de la decisión judicial, es una propuesta que trata de identificar aquellas condiciones mínimas que debe contener una decisión judicial para adquirir la categoría de racional, en el sentido de lo razonable.
Güette Hernández, David Modesto
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Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Ética y decisión racional.[Reseña]
, 2002 Reseña de Gilberto GUTIÉRREZ, Ética y decisión racional, Ed. Síntesis, «Col.
Sánchez-Migallón, S. (Sergio)
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CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Transparencias métodos de decisión empresarial
Conjunto de transparencias para las clases de la asignatura de Métodos de Decisión ...
Sánchez Martín, María Mercedes
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Modelos y Herramientas de Decisión : Guía Business Case 2018 [PDF]
, 2017 Guía para desarrollo Business Case de Modelos y Herramientas de Decisión.
Bautista Valhondo, Joaquín
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Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source