Results 131 to 140 of about 3,683,743 (248)
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Familias refugiadas iraquíes en Jordania: la búsqueda activa de soluciones [PDF]
, 2016 Para los refugiados iraquíes en Jordania la decisión de partir hacia Europa se ve muy influida por su experiencia mientras esperan en esta ...
Twigt, Mirjam A.
core +1 more source
Molecular cancer prevention: Intercepting disease
Molecular Oncology, EarlyView.Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
Proceso de decisión basado en la función de esparcimiento [PDF]
, 1999 First published in Revista de la Real Academia de Ciencias Exactas, Físicas y Naturales. Serie A. Matemáticas in 93, 4 (1999) published by the Real Academia de Ciencias Exactas, Físicas y Naturales.En este artículo, se estudia un proceso de decisión de ...
Fernández Ponce, José María +2 more
core +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Tecnología y Ciencia, 2018 El presente trabajo se propone analizar la aplicación de una herramienta de software basada en lógica difusa, para la identificación de la localización sustentable de cuatro parques industriales ubicados en la provincia de Córdoba.
Marcelo A. Tavella +2 more
doaj
Modelo de ayuda a la decisión en transporte intermodal [PDF]
, 2007 La posición estratégica que ocupa el transporte intermodal de mercancías está recogida en distintos planes y políticas. No obstante y pese a ello, este modo de transporte no termina de consolidarse como una realidad competitiva al transporte por ...
Delgado Rivas, Carmen María +3 more
core
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source