Results 131 to 140 of about 3,649,113 (248)

Elección racional: voto obligatorio y venta del voto en Colombia [PDF]

open access: yes, 2017
Artículo de reflexiónEn el artículo se hace un ejercicio en el que se utiliza la teoría de la decisión racional para explicar porque en las elecciones, la escogencia de un determinado candidato y la determinación de vender el voto, son productos de las ...
Angarita-Cala, Francisco
core  

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Diferenciación, Inclusión/Exclusión y Cohesión en la Sociedad Moderna.

open access: yesRevista CIS, 2018
En la sociedad moderna, las múltiples relaciones entre distintos sistemas, organizaciones, redes e interacciones, forman complejas constelaciones sociales que no pueden ser adecuadamente descritas por medio de la distinción binaria inclusión/exclusión ...
Aldo Mascareño
doaj  

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Inmigración ilegal, aplicación de la ley en la frontera y salarios relativos: elementos de juicio sobre las detenciones en la frontera entre EE.UU. y México [PDF]

open access: yes
(Disponible en idioma inglés únicamente) En este trabajo se analizan los factores determinantes de la inmigración ilegal hacia EE. UU. desde México desde 1976 hasta 1995.
Antonio Spilimbergo, Gordon H. Hanson
core  

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

open access: yesFEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim   +11 more
wiley   +1 more source

La franquicia, ¿una oportunidad de negocio?. (Caso de estudio) [PDF]

open access: yes
EN ESTE CASO SE PRESENTAN LAS SIGUIENTES SITUACIOES: En este caso se plasma la decisión de inversión de una persona del común, que vive la situación actual del país y que por cuestiones de la recesión económica y otros factores de orden político que vive
Andrés Jimenez Mosquera   +2 more
core  

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

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