Results 71 to 80 of about 10,061,461 (399)
Analogy in Decision Making [PDF]
Mathematics of Operations Research, 2015 In the context of decision making under uncertainty, I formalize the concept of analogy: an analogy between two decision problems is a mapping that transforms one problem into the other while preserving the problem’s structure. After identifying the basic structure of a decision problem, I introduce the concepts of analogical reasoning operator and of
openaire +3 more sources
FEBS Letters, EarlyView.In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali +3 more
wiley +1 more source
Reviewable Automated Decision-Making: A Framework for Accountable Algorithmic Systems [PDF]
ACM Conference on Fairness, Accountability, and Transparency
(FAccT 21), March 2021, Virtual Event, Canada, 2021 This paper introduces reviewability as a framework for improving the accountability of automated and algorithmic decision-making (ADM) involving machine learning. We draw on an understanding of ADM as a socio-technical process involving both human and technical elements, beginning before a decision is made and extending beyond the decision itself ...
arxiv
, 2011 The self-centeredness of modern organizations leads to environmental destruction and human deprivation. The principle of responsibility developed by Hans Jonas requires caring for the beings affected by our decisions and actions.
Zsolnai, László
core
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FEBS Letters, EarlyView.FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac +3 more
wiley +1 more source
A heuristic approach for lactate threshold estimation for training decision-making: An accessible and easy to use solution for recreational runners [PDF]
, 2019 In this work, a heuristic as operational tool to estimate the lactate threshold and to facilitate its integration into the training process of recreational runners is proposed. To do so, we formalize the principles for the lactate threshold estimation from empirical data and an iterative methodology that enables experience based learning. This strategy
arxiv +1 more source
BMJ Open, 2022 Objective To examine the impact of the government communicating uncertainties relating to COVID-19 vaccine effectiveness on vaccination intention and trust after people are exposed to conflicting information.Design Experimental design where participants ...
Eleonore Batteux +3 more
doaj +1 more source
FEBS Letters, EarlyView.Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi +3 more
wiley +1 more source
Decision-making difficulties mediate the association between poor emotion regulation and eating disorder symptoms in adolescence [PDF]
, 2022 BACKGROUND: The emergence of eating problems during childhood increases the risk for eating disorders (EDs) during young adulthood. Previous studies highlight a relationship between poor self-regulation and onset of eating pathology.
Flouri, Eirini +2 more
core
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source