Results 41 to 50 of about 3,307,600 (301)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

A Comparative Analysis of Classical Models for Crisis Management [PDF]

open access: yesAnnals of Dunarea de Jos University. Fascicle I : Economics and Applied Informatics
This article presents a comparative analysis of two significant theoretical models from decision-making literature. The models analyzed are the decision strategy selection model developed by Beach and Mitchell, and the strategic decision-making model in ...
Ionica Simbanu, Liliana Mihaela Moga
doaj   +1 more source

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait   +23 more
wiley   +1 more source

The analysis of the capacity of the selected measures of decision-making models in companies

open access: yesCopernican Journal of Finance & Accounting, 2015
The paper aims at the analysis of the information capacity of selected instruments of the assessment of decision-making models in the analyzed companies. In the paper there are presented the idea and concepts of decision-making models.
Helena Kościelniak   +3 more
doaj   +3 more sources

Neutrosophic UP (BCC)-Subalgebras of Several Types: A Threshold-Based Analysis in UP (BCC)-Algebras [PDF]

open access: yesNeutrosophic Sets and Systems
This study provides an extensive investigation into neutrosophic subalgebras within the context of BCC-algebras, establishing a new framework for their classification.
Aiyared Iampan, Neelamegarajan Rajesh
doaj   +1 more source

Implementation of Stochastic Analysis in Corporate Decision-Making Models

open access: yesMathematics, 2021
The stochastic approach as a method for modeling factor systems of interrelationships of economic activity aspects allows minimizing managerial errors against the background of company growth and expansion of operating activities.
Jin-Biao Lu   +4 more
doaj   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson   +3 more
wiley   +1 more source

An ES process framework for understanding the strategic decision making process of ES implementations [PDF]

open access: yes, 2001
Enterprise systems (ES) implementations are regarded costly, time and resource consuming and have a great impact on the organization in terms of the risks they involve and the opportunities they provide. The steering committee (SC) represents the group
Shakir, Maha
core  

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski   +9 more
wiley   +1 more source

Topological Models of Rough Sets and Decision Making of COVID-19

open access: yesComplexity, 2022
The basic methodology of rough set theory depends on an equivalence relation induced from the generated partition by the classification of objects.
Mostafa A. El-Gayar   +1 more
doaj   +1 more source

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