Results 201 to 210 of about 15,781,096 (290)

The decision-making process in general practice of when to use antibiotics to treat acute rhinosinusitis. [PDF]

Scand J Prim Health Care
Christensen TV, Plejdrup Hansen M, Jensen MSA, Hoffmann Merrild C.   +3 more
europepmc   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Decision-making process in game sports: what do top-level players think of current research? [PDF]

Front Sports Act Living
Magnaguagno L, Beck D.
europepmc   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

A medico-legal approach to developing a structured decision-making process for patients refusing blood transfusions. [PDF]

Front Public Health
Tattoli L, Santovito D.
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

The decision-making process in the choice of VBAC: Facilitators and barriers from women's perception, a systematic review. [PDF]

Eur J Midwifery
Cosmai G, Biondini M, Panzeri M, Serafini M, Lambicchi L, Locatelli A, Nespoli A, Fumagalli S.   +7 more
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

'I had no choice!' Challenges in the informed consent and decision-making process for allogeneic stem cell transplantation: a qualitative method triangulation. [PDF]

Stem Cell Res Ther
Nowak A, Nadolny S, Jahn F, Schaffrath J, Müller LP, Schildmann J.   +5 more
europepmc   +1 more source