Results 161 to 170 of about 193,992 (310)

Modelling the demographic impact of HIV/AIDS in South Africa and the likely impact of interventions [PDF]

This paper describes an approach to incorporating the impact of HIV/AIDS and the effects of HIV/AIDS prevention and treatment programmes into a cohort component projection model of the South African population.
Leigh F. Johnson, Rob Dorrington
core  

Correction: Decision aids for the care of patients with multimorbidity: a systematic review. [PDF]

BMC Prim Care
Chen Y, He R, Chen Z, Bai Y, Yang C.
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Shared decision-making and patient decision aids in knee osteoarthritis: a scoping review. [PDF]

Knee Surg Relat Res
Wang E, Stefanski A, Chow TKD, Spencer A, Thompson K, Gifford S.   +5 more
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Availability, acceptability and adoption of decision aids for HIV prevention and contraception for young people: a scoping review protocol. [PDF]

BMJ Open
Kabonga I, Kuguyo O, Mancitshana L, Chidhanguro K, Munhenzva S, Masiyambiri F, Ruhode N, Mangenah C, Sibanda E.   +8 more
europepmc   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Decision aids in patients with osteoporosis: A scoping review. [PDF]

PLoS One
Fang Y, Jia Q, Dai Y, Li S.
europepmc   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

AIDS CASE SURVEILLANCE IN ETHIOPIA: OCTOBER 31, 1993

, 2017
INTRODUCTIONThis report is published by the Department of AIDS Control on a monthly basis. The major objectives of the publication are to:* Notify the current status of AIDS epidemic in the country , and provide information which has prominence in ...
National AIDS Control Programme Ministry of Health
core