Results 231 to 240 of about 906,473 (303)

Lung cancer screening completion among patients using decision aids: a systematic review and meta-analysis. [PDF]

Cancer Causes Control
Antigua-Made A, Nguyen S, Rashidi A, Chen WP, Ziogas A, Sadigh G.   +5 more
europepmc   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Dissemination of Decision Aids about Hip and Knee Osteoarthritis to Spanish-Speaking Adults through Social Media. [PDF]

MDM Policy Pract
Valentine KD, Marques F, Chen AF, Simmons L, Sepucha KR.   +4 more
europepmc   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Development and pilot testing of the Population And ContExt adaption of decision aids (PACE) framework. [PDF]

PEC Innov
Dolan H, Bateson D, Li M, Thompson R, Tam CWM, Bonner C, Trevena L.   +6 more
europepmc   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Comparative Effectiveness of Decision Aids for Cancer-Screening Decision Making: An Overview of Reviews. [PDF]

J Gen Intern Med
Hibino M, Hamashima C, Hirosue M, Iwata M, Terasawa T.   +4 more
europepmc   +1 more source

Decision aids for female BRCA mutation carriers: a scoping review. [PDF]

BMJ Open
McGarrigle SA, Prizeman G, Spillane C, Byrne N, Drury A, Polus M, Mockler D, Connolly EM, Brady AM, Hanhauser YP.   +9 more
europepmc   +1 more source

Systematic review to understand users perspectives on AI-enabled decision aids to inform shared decision making. [PDF]

NPJ Digit Med
Hassan N, Slight R, Bimpong K, Bates DW, Weiand D, Vellinga A, Morgan G, Slight SP.   +7 more
europepmc   +1 more source

Exploring mobility patterns and social health of older Canadians living at home to inform decision aids about housing: A mixed-methods study. [PDF]

PLoS One
Mochcovitch D, Jones A, Goutte J, Plourde KV, de Carvalho Corôa R, Elf M, Meijering L, Sturge J, Bérubé P, Roche S, Guay-Bélanger S, Légaré F.   +11 more
europepmc   +1 more source