Results 91 to 100 of about 98,988 (307)

Is intermittent short-course anti-TB regimen as efficient and safe as daily anti-TB regimen for treating childhood TB?

open access: yesJournal of Family Medicine and Primary Care, 2015
Childhood tuberculosis (TB) is a common clinical condition in low- and middle-income nations like India where TB is endemic. Different guidelines vary in the recommendations on treatment regimes for childhood TB. Apart from clinical outcomes the decision
Soumyadeep Bhaumik
doaj   +1 more source

Implications of Conditional Inconstitutional Decisions in The Constitutional Court Decision

open access: yesJurnal Konstitusi, 2023
This research focuses on the decision of Constitutional Court Number 91/PUU-XVIII/2020, which states that Law Number 11 of 2020 concerning Job Creation is unconstitutional because of a formal flaw in its formation. This study aims to answer two questions.
openaire   +2 more sources

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

The implication of a term of good faith in commercial leases — A brief response

open access: yes, 2003
By way of response to Professor Duncan's article,1 this article examines the theoretical basis for the implication of contractual terms, particularly the implication of a term at law.
Dixon, William M.
core  

A thorough study of interrelationship in fuzzy implication axioms

open access: yes, 2010
A fuzzy implication is an extension of the classical binary implication in fuzzy logic that plays an important role in the approximate reasoning process and in decision making applications.
Ruan, Da   +3 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Interpretation and Implication

open access: yes, 2018
This research article considers the difference between interpretation and implication, and the status of the Privy Council decision Attorney-General of Belize v Belize Telecom in New Zealand, in the context of an upcoming Supreme Court ...
Connell, Simon
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

An Investment Criterion Incorporating Real Options [PDF]

open access: yes
Investment in infrastructure such as the information and communication technology sector requires large, substantial amounts, most of which are sunk or irreversible.
Paul RAPPOPORT   +2 more
core  

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