Results 51 to 60 of about 9,040,288 (288)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
A review of computer-assisted assessment [PDF]
, 2005 Pressure for better measurement of stated learning outcomes has resulted in a demand for more frequent assessment. The resources available are seen to be static or dwindling, but Information and Communications Technology is seen to increase productivity ...
Gráinne Conole +4 more
core +1 more source
Radiomics: the facts and the challenges of image analysis
European Radiology Experimental, 2018 Radiomics is an emerging translational field of research aiming to extract mineable high-dimensional data from clinical images. The radiomic process can be divided into distinct steps with definable inputs and outputs, such as image acquisition and ...
Stefania Rizzo +6 more
doaj +1 more source
Anytime collaborative brain–computer interfaces for enhancing perceptual group decision-making
Scientific Reports, 2021 In this paper we present, and test in two realistic environments, collaborative Brain-Computer Interfaces (cBCIs) that can significantly increase both the speed and the accuracy of perceptual group decision-making. The key distinguishing features of this
Saugat Bhattacharyya +4 more
doaj +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Participatory Design in Environmental Contexts: The Influence of Topic-Related Attitudes on Ideation
Interaction Design and Architecture(s)Creativity support tools (CSTs) play a fundamental role in supporting creativity in human-computer interaction (HCI). The rapid development of artificial intelligence (AI), particularly Large Language Models (LLMs), has significantly transformed ...
Umut Tasa +7 more
doaj +1 more source
The preconditions for computer-assisted decision-making in tomorrow’s schools [PDF]
, 1997 This paper is a summary of a multi-session group discussion among the listed authors in which they deal with three broad questions: What sorts of decisions need to be made in schools? What kinds of computer assistance would be helpful? What are the barriers to obtaining this assistance?
P. Hogenbirk +4 more
openaire +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source